Evidence map›Paper›PMID 38813489›Full record

ReviewTurkish journal of medical sciences2023

Long noncoding RNAs in pancreas cancer: from biomarkers to therapeutic targets.

Esra Güzel Tanoğlu, Seyfure Adigüzel, Alpaslan Tanoğlu, Zehra Betül Aydin, Gülizar Hocaoğlu, Samet Ebinç

Abstract readReview
In one paragraph

Review in Turkish journal of medical sciences, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Article
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Esra Güzel TanoğluDepartment of Molecular Biology and Genetics, Hamidiye Institute of Health Sciences, University of Health Sciences, İstanbul, Turkiye.ORCID https://orcid.org/0000-0002-0909-8935
Seyfure AdigüzelDepartment of Molecular Biology and Genetics, Hamidiye Institute of Health Sciences, University of Health Sciences, İstanbul, Turkiye.ORCID https://orcid.org/0000-0001-9911-0231
Alpaslan TanoğluDepartment of Internal Medicine, Division of Gastroenterology, School of Medicine, Bahçeşehir University, İstanbul, Turkiye.ORCID https://orcid.org/0000-0002-7477-6640
Zehra Betül AydinDepartment of Molecular Biology and Genetics, Hamidiye Institute of Health Sciences, University of Health Sciences, İstanbul, Turkiye.ORCID https://orcid.org/0000-0002-3766-0366
Gülizar HocaoğluDepartment of Molecular Biology and Genetics, Hamidiye Institute of Health Sciences, University of Health Sciences, İstanbul, Turkiye.ORCID https://orcid.org/0000-0003-3933-6647
Samet EbinçDepartment of Molecular Biology and Genetics, Hamidiye Institute of Health Sciences, University of Health Sciences, İstanbul, Turkiye.ORCID https://orcid.org/0000-0002-7573-8101

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Long noncoding RNAs (lncRNAs) are noncoding RNA molecules with a heterogeneous structure consisting of 200 or more nucleotides. Because these noncoding RNAs are transcribed by RNA polymerase II, they have properties similar to messenger RNA (mRNA). Contrary to popular belief, the term "ncRNA" originated before the discovery of microRNAs. LncRNA genes are more numerous than protein-coding genes. They are the focus of current molecular research because of their pivotal roles in cancer-related processes such as cell proliferation, differentiation, and migration. The incidence of pancreatic cancer (PC) is increasing around the world and research on the molecular aspects of PC are growing. In this review, it is aimed to provide critical information about lncRNAs in PC, including the biological and oncological behaviors of lncRNAs in PC and their potential application in therapeutic strategies and as diagnostic tumor markers.

Indexed as

Biomarkers, TumorPancreatic NeoplasmsRNA, Long NoncodingGene Expression Regulation, NeoplasticHumansBiomarkers, TumorRNA, Long NoncodingbiomarkercancerLong noncoding RNApancreaspancreas cancer

Identifiers

PMID38813489
PMCPMC10760575

What Socratic holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.