Evidence map›Paper›PMID 38816657›Full record

SynthesisArchives of osteoporosis2024

Association between a history of major osteoporotic fractures and subsequent hip fracture: a systematic review and meta-analysis.

Takashi Ariie, Norio Yamamoto, Yusuke Tsutsumi, Shuri Nakao, Akihiro Saitsu, Takahiro Tsuge, Haruka Tsuda, Yuki Nakashima, Takanori Miura, Yousuke Bandai and 2 more

Abstract readMeta-AnalysisSystematic Review
PubMed Publisher
In one paragraph

Synthesis in Archives of osteoporosis, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed.

  1. Article
  2. Relationship between typical fall patterns and fall-related fractures in older Japanese adults.Proceedings of the Japan Academy. Series B, Physical and biological sciences · 2025
    Article
  3. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

12 authors.

Takashi AriieDepartment of Physical Therapy, School of Health Sciences at Fukuoka, International University of Health and Welfare, 137-1 Enokizu, Okawa-Shi, Fukuoka, 831-8501, Japan. tks.ar1212@gmail.com.
Norio YamamotoScientific Research WorkS Peer Support Group (SRWS-PSG), Osaka, Japan.
Yusuke TsutsumiScientific Research WorkS Peer Support Group (SRWS-PSG), Osaka, Japan.
Shuri NakaoScientific Research WorkS Peer Support Group (SRWS-PSG), Osaka, Japan.
Akihiro SaitsuScientific Research WorkS Peer Support Group (SRWS-PSG), Osaka, Japan.
Takahiro TsugeScientific Research WorkS Peer Support Group (SRWS-PSG), Osaka, Japan.
Haruka TsudaScientific Research WorkS Peer Support Group (SRWS-PSG), Osaka, Japan.
Yuki NakashimaScientific Research WorkS Peer Support Group (SRWS-PSG), Osaka, Japan.
Takanori MiuraScientific Research WorkS Peer Support Group (SRWS-PSG), Osaka, Japan.
Yousuke BandaiScientific Research WorkS Peer Support Group (SRWS-PSG), Osaka, Japan.
Ryota OkobaDepartment of Physical Therapy, Faculty of Health and Welfare, Prefectural University of Hiroshima, Hiroshima, Japan.
Shunsuke TaitoScientific Research WorkS Peer Support Group (SRWS-PSG), Osaka, Japan.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

purposeA history of fractures involving the distal radius, proximal humerus, spine, and hip may be associated with the incidence of subsequent hip fractures in older people. However, a comprehensive summary of this association using a rigorous methodology is lacking. Our objective was to systematically review the literature and examine the association between four major osteoporotic fractures and subsequent hip fractures in individuals aged ≥ 50 years.

methodsWe searched MEDLINE, Embase, CENTRAL, ICTRP, and ClinicalTrials.gov on February 15, 2023. The search included cohort or case-control studies investigating the association between these four types of osteoporotic fractures and subsequent hip fractures. We pooled the hazard ratios (HRs) with 95% confidence intervals (CI) using the random-effects model. We used the Quality In Prognosis Studies tool to assess the risk of bias in the included studies, and the grading of recommendations assessment, development, and evaluation approach to determine the certainty of evidence.

resultsThe selection process identified 48 studies for qualitative synthesis and 23 studies (2,239,217 participants) for meta-analysis. The overall methodological quality had a low risk of bias in 65% of the included studies. The association between a history of major osteoporotic fractures and subsequent hip fracture varied, with a high certainty of evidence for a history of proximal humerus and hip fractures (HR 2.02, 95% CI 1.75-2.33 and 2.86, 95% CI 1.92-4.25, respectively), moderate certainty for distal radius fractures (HR 1.66, 95% CI 1.53-1.81), and low certainty for spine fractures (HR 1.53, 95% CI 1.38-1.69).

conclusionsIn conclusion, a history of major osteoporotic fractures, particularly distal radius, proximal humerus, and hip fractures, is associated with subsequent hip fractures in older adults. Further research is needed to verify the association between a history of spine fracture and subsequent hip fractures. PROTOCOL REGISTRATION: Open Science Framework ( https://osf.io/7fjuc ).

Indexed as

Hip FracturesOsteoporotic FracturesAgedHumansIncidenceRisk FactorsMeta-analysisOsteoporosisPrognosisSubsequent fracturesSystematic review

Identifiers

PMID38816657

What Socratic holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.