Evidence map›Paper›PMID 38818916›Full record

ReviewCurrent medicinal chemistry2025

Antimalarial Drug Discovery from Natural and Synthetic Sources.

Nik Nur Solehah Fitri Nik Mohd Azam, Shatrah Othman, Yeun-Mun Choo

Abstract readReview
PubMed Publisher
In one paragraph

Review in Current medicinal chemistry, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors.

Nik Nur Solehah Fitri Nik Mohd AzamDepartment of Chemistry, University of Malaya, Kuala Lumpur, 50603, Malaysia.
Shatrah OthmanDepartment of Molecular Medicine, Faculty of Medicine, Universiti Malaya, Kuala Lumpur, 50603, Malaysia.
Yeun-Mun ChooDepartment of Chemistry, University of Malaya, Kuala Lumpur, 50603, Malaysia.ORCID 0000-0001-9891-5898

Funding

Ministry of Higher Education (MOHE), Malaysia IF070-2020
6 · The paper itself

Abstract

Malaria remains a significant global health threat despite extensive efforts aimed at its eradication. Numerous challenges persist in eliminating the disease, chief among them being the parasite's ability to mutate, resulting in drug resistance. The discovery of antimalarial drugs has relied on both phenotypic and target-based approaches. While phenotypic screening has identified promising candidates, target-based methods offer a more precise approach by leveraging chemically validated targets and computational tools. Analysis of

Indexed as

AntimalarialsBiological ProductsDrug DiscoveryMalariaPlasmodiumAnimalsHumansAntimalarialsBiological Productsantimalarialdrug developmenthypoglycemia.Malarianatural productstarget-based drug discovery

Identifiers

What Socratic holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.