Evidence map›Paper›PMID 38819432›Full record

ArticleCancer medicine2024

Prevalence and biopsychosocial indicators of fatigue in cancer patients.

Elisabeth L Zeilinger, Irina Zrnic-Novakovic, Claudia Oppenauer, Matthäus Fellinger, Matthias Knefel, Matthias Unseld, Theresa Wagner, Simone Lubowitzki, Rupert Bartsch, Sabine Zöchbauer-Müller and 4 more

Abstract read
In one paragraph

Article in Cancer medicine, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 13 papers, 2 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
13citing papers in PubMed, 2 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

13 citing papers in PubMed, 2 syntheses or guidelines pooled it.

  1. Pooled it
  2. Pooled it
  3. Article
  4. From traditional warming and tonifying to psychoneuroimmunology: theoretical reconstruction and clinical application of moxibustion for cancer-related fatigue.Supportive care in cancer : official journal of the Multinational Association of Supportive Care in Cancer · 2026
    Review
  5. Article
  6. Article
  7. Article
  8. Investigating fatigue in adults with neuroendocrine neoplasms using a biopsychosocial model.Supportive care in cancer : official journal of the Multinational Association of Supportive Care in Cancer · 2025
    Observational
  9. Article
  10. Article
  11. Article
  12. Reflection on the Human Experience of Cancer-Related Fatigue.Journal of cancer education : the official journal of the American Association for Cancer Education · 2025
    Article
  13. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

14 authors.

Elisabeth L ZeilingerDivision of Hematology and Hemostaseology, Department of Medicine I, Medical University of Vienna, Vienna, Austria.ORCID 0000-0002-0625-500X
Irina Zrnic-NovakovicDepartment of Clinical and Health Psychology, Faculty of Psychology, University of Vienna, Vienna, Austria.
Claudia OppenauerDivision of Clinical Psychology, Department of Psychology and Psychodynamics, Karl Landsteiner University of Health Sciences, Krems, Austria.
Matthäus FellingerClinical Division of Social Psychiatry, Department of Psychiatry and Psychotherapy, Medical University of Vienna, Vienna, Austria.
Matthias KnefelDivision of Hematology and Hemostaseology, Department of Medicine I, Medical University of Vienna, Vienna, Austria.ORCID 0000-0003-0632-0673
Matthias UnseldDepartment of Clinical Research SBG, Academy for Ageing Research, Haus der Barmherzigkeit, Vienna, Austria.
Theresa WagnerDepartment of Clinical and Health Psychology, Faculty of Psychology, University of Vienna, Vienna, Austria.
Simone LubowitzkiDivision of Hematology and Hemostaseology, Department of Medicine I, Medical University of Vienna, Vienna, Austria.
Rupert BartschDivision of Oncology, Department of Internal Medicine I, Medical University of Vienna, Vienna, Austria.
Sabine Zöchbauer-MüllerDivision of Oncology, Department of Internal Medicine I, Medical University of Vienna, Vienna, Austria.
Markus RadererDivision of Oncology, Department of Internal Medicine I, Medical University of Vienna, Vienna, Austria.
Philipp B StaberDivision of Hematology and Hemostaseology, Department of Medicine I, Medical University of Vienna, Vienna, Austria.
Peter ValentDivision of Hematology and Hemostaseology, Department of Medicine I, Medical University of Vienna, Vienna, Austria.
Alexander GaigerDivision of Hematology and Hemostaseology, Department of Medicine I, Medical University of Vienna, Vienna, Austria.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

introductionSymptoms of cancer-related fatigue (CRF) can have a significant impact on patients' quality of life and treatment adherence. We aimed to investigate the relationship between CRF and multiple psychosocial and somatic indicators within a large mixed cancer sample.

methodsIn this cross-sectional study, N = 1787 outpatients with cancer were assessed for CRF, pain, anxiety, and depression using validated screening instruments. We further obtained clinical parameters (Hb, CRP, creatinine, leukocytes, ASAT, and ALAT), sociodemographic data (age, gender, income, education level, marital status, parenthood, and living area), and lifestyle factors. Multivariate linear regression models were applied to estimate the impact of each indicator on CRF.

resultsOverall, 90.6% of patients experienced some CRF, with 14.8% experiencing severe CRF. No gender difference was found in the prevalence of CRF. Patients with higher levels of pain, depressive symptoms, and lower Hb levels had significantly higher levels of CRF (p

conclusionThe present results demonstrate a high prevalence of CRF and highlight that not only somatic and psychosocial factors, but also lifestyle factors prior to diagnosis appear to be associated with the etiology and persistence of CRF. To effectively treat CRF, a biopsychosocial, personalized approach is recommended.

Indexed as

DepressionFatigueNeoplasmsQuality of LifeAdultAgedAnxietyCross-Sectional StudiesFemaleHumansMaleMiddle AgedPrevalencebiopsychosocial modelsfatiguemental healthneoplasmspsycho‐oncology

Identifiers

PMID38819432
PMCPMC11141333

What Socratic holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.