Evidence map›Paper›PMID 38819614›Full record

ArticleNeurology and therapy2024

Photophobia and Visual Triggers in Vestibular Migraine.

Xiaodong Zou, Jiahui He, Mengting Zhou, Fangling Zhao, Xiulin Tian, Xiaopei Xu, Wenwu Hong, Faming Wang, Juanyan Chen, Chenghui Qin and 5 more

Registry-linked trialAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Neurology and therapy, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT04939922 (China Headache and Vertigo Registry Study), which is not on this map. Cited by 8 papers.

0numbers the graph read from it
0cells of the map it votes in
8citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT04939922 recruitingnot on this map

China Headache and Vertigo Registry Study

Typeobservational_patient_registrySponsorSecond Affiliated Hospital, Zhejiang University, School of MedicineRan2017 to 2050Enrolled10,000ConditionsHeadache Disorders, Primary, Headache Disorders, Secondary, Migraine, Tension-Type Headache
3 · Its place in the literature

Who cites it

8 citing papers in PubMed.

  1. Article
  2. Article
  3. Review
  4. Article
  5. Article
  6. Review
  7. Article
  8. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

15 authors.

Xiaodong Zou *Department of Neurology, Tongde Hospital of Zhejiang Province, Hangzhou, 310012, Zhejiang, China.
Jiahui He *Department of Neurology, Second Affiliated Hospital, School of Medicine, Zhejiang University, Hangzhou, 310003, Zhejiang, China.
Mengting Zhou *Department of Neurology, Second Affiliated Hospital, School of Medicine, Zhejiang University, Hangzhou, 310003, Zhejiang, China.
Fangling ZhaoDepartment of Neurology, Second Affiliated Hospital, School of Medicine, Zhejiang University, Hangzhou, 310003, Zhejiang, China.
Xiulin TianDepartment of Neurology, Second Affiliated Hospital, School of Medicine, Zhejiang University, Hangzhou, 310003, Zhejiang, China.
Xiaopei XuDepartment of Neurology, Second Affiliated Hospital, School of Medicine, Zhejiang University, Hangzhou, 310003, Zhejiang, China.
Wenwu HongDepartment of Neurology, Tiantai People's Hospital of Zhejiang Province, Tiantai, 317200, Zhejiang, China.
Faming WangDepartment of Neurology, Tiantai People's Hospital of Zhejiang Province, Tiantai, 317200, Zhejiang, China.
Juanyan ChenDepartment of Neurology, Dongyang People's Hospital, Dongyang, 322103, Zhejiang, China.
Chenghui QinDepartment of Neurology, Affiliated Hospital of Shaoxing University, Shaoxing, 312099, Zhejiang, China.
Jinjin XiaDepartment of Neurology, Changxing People's Hospital of Zhejiang Province, Changxing, 313199, Zhejiang, China.
Yuying XieDepartment of Neurology, Shanghang County Hospital, Shanghang, 364299, Fujian, China.
Yujin XiaoDepartment of Neurology, Jiaxing Hospital of Traditional Chinese Medicine, Jiaxing, 314033, Zhejiang, China.
Kaiming LiuDepartment of Neurology, Second Affiliated Hospital, School of Medicine, Zhejiang University, Hangzhou, 310003, Zhejiang, China. 2314411@zju.edu.cn.
Liang GuoDepartment of Ophthalmology, Qilu Hospital of Shandong University, Jinan, 250012, Shandong, China. liangg@sdu.edu.cn.

Funding

Key Research and Development Program of Zhejiang Province 2024C03007Natural Science Foundation of Zhejiang Province LY19H090025Public Welfare Foundation of Zhejiang Science and Technology Agency LGF20H160014
6 · The paper itself

Abstract

introductionVestibular migraine (VM) is a prevalent vestibular disorder characterized by episodic vertigo. However, the relationship between photophobia and visual triggers in VM remains unexplored. We investigated the correlation of photophobia during the VM attack with interictal photosensitivity and visually triggering dizziness in patients with VM.

methodsWe enrolled patients diagnosed with VM, with or without photophobia, across seven specialized vertigo and headache clinics in China. Healthy individuals were also included as a control group. Using a cross-sectional survey design, we collected data related to light intensity and dizziness frequency triggered by flicker, glare, and eyestrain using the Headache Triggers Sensitivity and Avoidance Questionnaire.

resultsA total of 366 patients were recruited. The photosensitivity and frequency of dizziness induced by flicker, glare, and eyestrain observed in patients with VM and photophobia were significantly elevated compared with those in patients without photophobia and control participants (P < 0.001). A significant positive correlation was observed between photosensitivity levels and dizziness frequency triggered by flicker, glare, and eyestrain in patients with VM and photophobia (P < 0.001).

conclusionsThis study unequivocally established a positive association of ictal photophobia with interictal photosensitivity and visually triggering dizziness, strongly advocating the need for further research on exposure-based therapies for managing VM. CLINICAL TRIALS REGISTRATION: ClinicalTrial.gov Identifier, NCT04939922, retrospectively registered, 14th June 2021.

Indexed as

DizzinessLight sensitivityPhotophobiaVestibular migraineVisual trigger

Identifiers

PMID38819614
PMCPMC11263323

What Socratic holds

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Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.