Evidence map›Paper›PMID 38820626›Full record

ArticleBiochemical and biophysical research communications2024

Physiological role for S-nitrosylation of RyR1 in skeletal muscle function and development.

Qi-An Sun, Zachary W Grimmett, Douglas T Hess, Lautaro G Perez, Zhaoxia Qian, Ruchi Chaube, Nicholas M Venetos, Bradley N Plummer, Kenneth R Laurita, Richard T Premont and 1 more

Abstract read
In one paragraph

Article in Biochemical and biophysical research communications, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed.

  1. Review
  2. The Ever-Expanding Influence of the Endothelial Nitric Oxide Synthase.Basic & clinical pharmacology & toxicology · 2025
    Review
  3. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors.

Qi-An SunInstitute for Transformative Molecular Medicine and Department of Medicine, Case Western Reserve University School of Medicine and University Hospitals Cleveland Medical Center, Cleveland, OH, 44106, USA.
Zachary W GrimmettInstitute for Transformative Molecular Medicine and Department of Medicine, Case Western Reserve University School of Medicine and University Hospitals Cleveland Medical Center, Cleveland, OH, 44106, USA.
Douglas T HessInstitute for Transformative Molecular Medicine and Department of Medicine, Case Western Reserve University School of Medicine and University Hospitals Cleveland Medical Center, Cleveland, OH, 44106, USA.
Lautaro G PerezDepartment of Surgery, Duke University School of Medicine, Durham, NC, 27710, USA.
Zhaoxia QianInstitute for Transformative Molecular Medicine and Department of Medicine, Case Western Reserve University School of Medicine and University Hospitals Cleveland Medical Center, Cleveland, OH, 44106, USA.
Ruchi ChaubeInstitute for Transformative Molecular Medicine and Department of Medicine, Case Western Reserve University School of Medicine and University Hospitals Cleveland Medical Center, Cleveland, OH, 44106, USA.
Nicholas M VenetosInstitute for Transformative Molecular Medicine and Department of Medicine, Case Western Reserve University School of Medicine and University Hospitals Cleveland Medical Center, Cleveland, OH, 44106, USA.
Bradley N PlummerHeart and Vascular Research Center, MetroHealth Campus of Case Western Reserve University, Cleveland, OH, 44109, USA.
Kenneth R LauritaHeart and Vascular Research Center, MetroHealth Campus of Case Western Reserve University, Cleveland, OH, 44109, USA.
Richard T PremontInstitute for Transformative Molecular Medicine and Department of Medicine, Case Western Reserve University School of Medicine and University Hospitals Cleveland Medical Center, Cleveland, OH, 44106, USA; Harrington Discovery Institute, University Hospitals Cleveland Medical Center, Cleveland, OH, 44106, USA.
Jonathan S StamlerInstitute for Transformative Molecular Medicine and Department of Medicine, Case Western Reserve University School of Medicine and University Hospitals Cleveland Medical Center, Cleveland, OH, 44106, USA; Harrington Discovery Institute, University Hospitals Cleveland Medical Center, Cleveland, OH, 44106, USA. Electronic address: jonathan.stamler@case.edu.

Funding

Redox Signalling by Nitric Oxide in Skeletal MuscleR01HL059130 · NHLBI · DUKE UNIVERSITY · PI STAMLER, JONATHAN S. · 1997 to 2011
$3.1M
NHLBI NIH HHS R01 HL059130
6 · The paper itself

Abstract

Excitation-contraction coupling in skeletal muscle myofibers depends upon Ca

Indexed as

Muscle, SkeletalRyanodine Receptor Calcium Release ChannelAnimalsCalciumCalcium SignalingCysteineMiceMice, TransgenicMuscle DevelopmentProtein Processing, Post-TranslationalCalciumCysteineryanodine receptor 1, mouseRyanodine Receptor Calcium Release ChannelExcitation-contraction couplingMuscle hypoxiaNitric oxideRyanodine receptorSarcoplasmic reticulumS-nitrosothiol

Identifiers

PMID38820626
PMCPMC12651786

What Socratic holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.