Evidence map›Paper›PMID 38826057›Full record

ReviewMicrocirculation (New York, N.Y. : 1994)2024

Perivascular Adipose Tissue and Uterine Artery Adaptations to Pregnancy.

Oluwatobiloba Osikoya, Nataliia Hula, Renée de Nazaré Oliveira da Silva, Styliani Goulopoulou

Abstract readReview
In one paragraph

Review in Microcirculation (New York, N.Y. : 1994), 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed.

  1. Endothelial Dysfunction in Preeclampsia: Focus on the Uteroplacental Circulation.Arteriosclerosis, thrombosis, and vascular biology · 2026
    Review
  2. Review
  3. Understanding Vascular Reactivity.Microcirculation (New York, N.Y. : 1994) · 2025
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors.

Oluwatobiloba OsikoyaDepartment of Physiology and Anatomy, University of North Texas Health Science Center at Fort Worth, Fort Worth, Texas, USA.
Nataliia HulaLawrence D. Longo, MD Center for Perinatal Biology, Department of Basic Sciences, Loma Linda University, Loma Linda, California, USA.
Renée de Nazaré Oliveira da SilvaLawrence D. Longo, MD Center for Perinatal Biology, Department of Basic Sciences, Loma Linda University, Loma Linda, California, USA.
Styliani GoulopoulouLawrence D. Longo, MD Center for Perinatal Biology, Department of Basic Sciences, Loma Linda University, Loma Linda, California, USA.ORCID 0000-0001-7636-8256

Funding

Preeclampsia and pre-clinical stages of maternal vascular dementiaR01HL146562 · NHLBI · UNIVERSITY OF NORTH TEXAS HLTH SCI CTR · PI GOULOPOULOU, STYLIANI · 2020 to 2024
$2.9M
NHLBI NIH HHS R01 HL146562
6 · The paper itself

Abstract

Pregnancy is characterized by longitudinal maternal, physiological adaptations to support the development of a fetus. One of the cardinal maternal adaptations during a healthy pregnancy is a progressive increase in uterine artery blood flow. This facilitates sufficient blood supply for the development of the placenta and the growing fetus. Regional hemodynamic changes in the uterine circulation, such as a vast reduction in uterine artery resistance, are mainly facilitated by changes in uterine artery reactivity and myogenic tone along with remodeling of the uterine arteries. These regional changes in vascular reactivity have been attributed to pregnancy-induced adaptations of cell-to-cell communication mechanisms, with an emphasis on the interaction between endothelial and vascular smooth muscle cells. Perivascular adipose tissue (PVAT) is considered the fourth layer of the vascular wall and contributes to the regulation of vascular reactivity in most vascular beds and most species. This review focuses on mechanisms of uterine artery reactivity and the role of PVAT in pregnancy-induced maternal vascular adaptations, with an emphasis on the uterine circulation.

Indexed as

Adaptation, PhysiologicalAdipose TissueUterine ArteryAnimalsFemaleHumansPregnancyadipose tissuegestationmaternal vascular functionuterine artery blood flow

Identifiers

PMID38826057
PMCPMC12313253

What Socratic holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.