Evidence map›Paper›PMID 38826410›Full record

ArticlebioRxiv : the preprint server for biology2024

Deep Transcriptomics Reveals Cell-Specific Isoforms of Pan-Neuronal Genes.

Zachery Wolfe, David Liska, Adam Norris

Abstract readPreprint
In one paragraph

Article in bioRxiv : the preprint server for biology, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

3 authors.

Zachery WolfeDepartment of Biological Sciences, Southern Methodist University, Dallas, TX 75205, United States.
David LiskaOffice of Information Technology, Southern Methodist University, Dallas, TX 75205, United States.
Adam NorrisDepartment of Biochemistry, University of California, Riverside, 3401 Watkins Drive, Boyce Hall, Riverside, CA, 92521, United States.ORCID 0000-0002-0570-7414

Funding

Dissecting RNA regulation in single cells and tissuesR35GM133461 · NIGMS · UNIVERSITY OF CALIFORNIA RIVERSIDE · PI Adam Norris · 2019 to 2026
$3.1M
COORDINATE CONTROL OF INDIVIDUAL NEURONAL TRANSCRIPTOMES BY TRANSCRIPTION FACTORS AND RNA BINDING PROTEINSR01NS111055 · NINDS · UNIVERSITY OF CALIFORNIA RIVERSIDE · PI NORRIS, ADAM · 2020 to 2024
$1.6M
NIGMS NIH HHS R35 GM133461NINDS NIH HHS R01 NS111055
6 · The paper itself

Abstract

Profiling gene expression in single neurons using single-cell RNA-Seq is a powerful method for understanding the molecular diversity of the nervous system. Profiling alternative splicing in single neurons using these methods is more challenging, however, due to low capture efficiency and sensitivity. As a result, we know much less about splicing patterns and regulation across neurons than we do about gene expression. Here we leverage unique attributes of the

Identifiers

PMID38826410
PMCPMC11142100

What Socratic holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.