ArticleHeliyon2024
Ampicillin detection using absorbance biosensors utilizing Mn-doped ZnS capped with chitosan micromaterials.
Article in Heliyon, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers.
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Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
6 citing papers in PubMed.
- A label-free impedimetric strategy using interdigitated electrodes for tetracycline detection in Milk.Food chemistry: X · 2026Article
- Fluorescent carbon dot-based biosensor for the rapid and sensitive detection of Escherichia coli DNA.Scientific reports · 2026Article
- Disposable non-enzymatic impedimetric biosensor using Mn-doped ZnS-chitosan nanocomposite for tetracycline detection.PloS one · 2026Article
- Reduced graphene oxide-based absorbance biosensors for detecting Escherichia coli DNA.Scientific reports · 2025Article
- A non-enzymatic doxycycline absorbance sensor based on manganese-doped zinc sulfide nanoparticles coated with chitosan.PloS one · 2025Article
- Enzyme-free biosensor utilizing chitosan-capped ZnS doped by Mn nanomaterials for tetracycline hydrochloride detection.Heliyon · 2024Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
3 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
The detection of ampicillin plays a crucial role in managing and monitoring its usage and resistance. This study introduces a simple and effective biosensor for ampicillin detection, utilizing the unique absorbance features of Mn-doped ZnS capped by chitosan micromaterials in conjunction with β-lactamase activity. The biosensors can detect ampicillin concentrations from 13.1 to 72.2 μM, with a minimum detection limit of 2.93 μM for sensors based on 300 mg/L of the sensing material. In addition, these sensors show high specificity for ampicillin over other antibiotics such as penicillin, tetracycline, amoxicillin, cephalexin, and a non-antibiotic-glucose. This specificity is demonstrated by an enhancing effect when beta-lactamase is used, as opposed to a quenching effect observed at 340 nm in the absorbance spectrum when no beta-lactamase is present. This research highlights the potential of affordable chitosan-capped Mn-doped ZnS micromaterials for detecting ampicillin through simple absorbance measurements, which could improve the monitoring of antibiotics in both clinical and environmental settings.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.