Evidence map›Paper›PMID 38827331›Full record

ArticleJID innovations : skin science from molecules to population health2024

Testing the Reliability of Optical Coherence Tomography to Measure Epidermal Thickness and Distinguish Volar and Nonvolar Skin.

Molly E Baumann, Nina Rossa Haddad, Alyssa Salazar, W Lee Childers, Shawn Farrokhi, Neil B Goldstein, Brad D Hendershot, Lisa Reider, Richard E Thompson, Michael S Valerio and 3 more

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in JID innovations : skin science from molecules to population health, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

13 authors.

Molly E BaumannResearch and Surveillance Section, Extremity Trauma and Amputation Center of Excellence, Defense Health Agency, Falls Church, Virginia, USA.
Nina Rossa HaddadDepartment of Dermatology, Johns Hopkins University School of Medicine, Baltimore, Maryland, USA.
Alyssa SalazarDepartment of Rehabilitation Medicine, Center for the Intrepid, Brooke Army Medical Center, San Antonio, Texas, USA.
W Lee ChildersResearch and Surveillance Section, Extremity Trauma and Amputation Center of Excellence, Defense Health Agency, Falls Church, Virginia, USA.
Shawn FarrokhiResearch and Surveillance Section, Extremity Trauma and Amputation Center of Excellence, Defense Health Agency, Falls Church, Virginia, USA.
Neil B GoldsteinResearch and Surveillance Section, Extremity Trauma and Amputation Center of Excellence, Defense Health Agency, Falls Church, Virginia, USA.
Brad D HendershotResearch and Surveillance Section, Extremity Trauma and Amputation Center of Excellence, Defense Health Agency, Falls Church, Virginia, USA.
Lisa ReiderJohns Hopkins Bloomberg School of Public Health, Baltimore, Maryland, USA.
Richard E ThompsonJohns Hopkins Bloomberg School of Public Health, Baltimore, Maryland, USA.
Michael S ValerioResearch and Surveillance Section, Extremity Trauma and Amputation Center of Excellence, Defense Health Agency, Falls Church, Virginia, USA.
Christopher L DearthResearch and Surveillance Section, Extremity Trauma and Amputation Center of Excellence, Defense Health Agency, Falls Church, Virginia, USA.
Luis A GarzaDepartment of Dermatology, Johns Hopkins University School of Medicine, Baltimore, Maryland, USA.
Major Extremity Trauma Research Consortium (METRC)

Funding

Retinoic acid synthesis induced by noncoding dsRNA controls RegenerationR01AR074846 · NIAMS · JOHNS HOPKINS UNIVERSITY · PI GARZA, LUIS ANDRES · 2019 to 2023
$2.3M
Injection of autologous volar fibroblasts to the stump site to allow pressure adaptation and enhanced prosthetic use in amputeesUH3AR079376 · NIAMS · JOHNS HOPKINS UNIVERSITY · PI Luis Andres Garza · 2023 to 2026
$2.1M
Injection of autologous volar fibroblasts to the stump site to allow pressure adaptation and enhanced prosthetic use in amputeesUG3AR079376 · NIAMS · JOHNS HOPKINS UNIVERSITY · PI GARZA, LUIS ANDRES · 2021 to 2021
$532k
Inhibition of Regeneration Restraining Pathways to Promote HealingR56AR082660 · NIAMS · JOHNS HOPKINS UNIVERSITY · PI GARZA, LUIS ANDRES · 2023 to 2023
$360k
NIAMS NIH HHS R01 AR074846NIAMS NIH HHS R56 AR082660NIAMS NIH HHS UG3 AR079376NIAMS NIH HHS UH3 AR079376
6 · The paper itself

Abstract

In persons with limb loss, prosthetic devices cause skin breakdown, largely because residual limb skin (nonvolar) is not intended to bear weight such as palmoplantar (volar) skin. Before evaluation of treatment efficacy to improve skin resiliency, efforts are needed to establish normative data and assess outcome metric reliability. The purpose of this study was to use optical coherence tomography to (i) characterize volar and nonvolar skin epidermal thickness and (ii) examine the reliability of optical coherence tomography. Four orientations of optical coherence tomography images were collected on 33 volunteers (6 with limb loss) at 2 time points, and the epidermis was traced to quantify thickness by 3 evaluators. Epidermal thickness was greater (

Indexed as

Epidermal thicknessNonvolar skinOptical coherence tomographyVolar skin

Identifiers

PMID38827331
PMCPMC11137746

What Socratic holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.