Evidence map›Paper›PMID 38828353›Full record

ArticleHeliyon2024

Fluorescent monitoring osteogenic differentiation of osteosarcoma cells with an aggregation-induced emission probe.

Junxiong Zhang, Zhongming Lai, Zhongmin Zhang, Shuai Zheng

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Heliyon, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors.

Junxiong ZhangDepartment of Orthopaedics, The First Affiliated Hospital, Southern Medical University, Academy of Orthopaedics, Guangdong Province, Guangzhou, 510515, China.
Zhongming LaiDepartment of Orthopaedics, The First Affiliated Hospital, Southern Medical University, Academy of Orthopaedics, Guangdong Province, Guangzhou, 510515, China.
Zhongmin ZhangDepartment of Orthopaedics, The First Affiliated Hospital, Southern Medical University, Academy of Orthopaedics, Guangdong Province, Guangzhou, 510515, China.
Shuai ZhengDepartment of Orthopaedics, The First Affiliated Hospital, Southern Medical University, Academy of Orthopaedics, Guangdong Province, Guangzhou, 510515, China.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Osteosarcoma is widely believed to be an osteogenic differentiation disorder. In recent years, to further understand this disease, a lot resources were poured into the potential link between differentiation defects and tumorigenesis. Long-term monitoring of the differentiation progress of osteosarcoma cells is of great importance. In order to better promote the research, we have developed a novel fluorescent probe called PTB-EDTA, which exhibits remarkable bio-compatibility and demonstrates high selectivity towards osteosarcoma cells. Not only is the PTB-EDTA is capable of live cell imaging while conventional histology requires to kill the cells, its fluorescence is also enhanced as the osteogenic differentiation proceeding. These properties make PTB-EDTA a promising tool for monitoring osteosarcoma cells.

Indexed as

Aggregation-induced emissionCalcium ionsFluorescenceOsteogenic differentiationOsteosarcoma

Identifiers

PMID38828353
PMCPMC11140698

What Socratic holds

Textmetadata
LicenceCC BY-NC
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.