Evidence map›Paper›PMID 38835104›Full record

Trial reportBMC psychology2024

Psychosocial predictors of health behavior adherence in heart-failure patients with comorbid depression: a secondary analysis of the Hopeful Heart trial.

Alba Carrillo, Bea Herbeck Belnap, Scott D Rothenberger, Robert Feldman, Bruce L Rollman, Christopher M Celano

Registry-linked trialAbstract readRandomized Controlled Trial
In one paragraph

Trial report in BMC psychology, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT02044211 (Blended Collaborative Care for Heart Failure and Co-Morbid Depression), which is not on this map. Cited by 6 papers.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT02044211 phase2 / phase3completednot on this map

Blended Collaborative Care for Heart Failure and Co-Morbid Depression

TypeinterventionalSponsorUniversity of PittsburghRan2014 to 2020Enrolled756ConditionsHeart Failure, Systolic, Depression, Cardiovascular DiseaseArmsCollaborative Care for Heart Failure, Collaborative Care for Depression
3 · Its place in the literature

Who cites it

6 citing papers in PubMed.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Alba CarrilloInstituto Polibienestar, University of Valencia, Valencia, Spain.
Bea Herbeck BelnapDivision of General Internal Medicine, Center for Research on Health Care, University of Pittsburgh School of Medicine, Pittsburgh, PA, USA.
Scott D RothenbergerDivision of General Internal Medicine, Center for Research on Health Care, University of Pittsburgh School of Medicine, Pittsburgh, PA, USA.
Robert FeldmanDivision of General Internal Medicine, Center for Research on Health Care, University of Pittsburgh School of Medicine, Pittsburgh, PA, USA.
Bruce L RollmanDivision of General Internal Medicine, Center for Research on Health Care, University of Pittsburgh School of Medicine, Pittsburgh, PA, USA.
Christopher M CelanoDepartment of Psychiatry, Massachusetts General Hospital, 125 Nashua Street, Suite 324, Boston, MA, 02114, USA. ccelano@mgh.harvard.edu.

Funding

Blended Collaborative Care for Heart Failure and Co-Morbid DepressionR01HL114016 · NHLBI · UNIVERSITY OF PITTSBURGH AT PITTSBURGH · PI ROLLMAN, BRUCE LAWRENCE · 2013 to 2017
$7.3M
A novel behavioral intervention to promote adherence in heart failureR01HL155301 · NHLBI · MASSACHUSETTS GENERAL HOSPITAL · PI CELANO, CHRISTOPHER M · 2021 to 2025
$3.8M
NHLBI NIH HHS R01HL114016NHLBI NIH HHS R01 HL155301NHLBI NIH HHS R01HL155301
6 · The paper itself

Abstract

backgroundDepression affects 20-30% of individuals with heart failure (HF), and it is associated with worse health outcomes independent of disease severity. One potential explanation is the adverse impact of depression on HF patients' adherence to the health behaviors needed to self-manage their condition. The aim of this study is to identify characteristics associated with lower adherence in this population, which could help to recognize individuals at higher risk and eventually tailor health behavior interventions to their needs.

methodsUsing data from a randomized, controlled, collaborative care treatment trial in 629 patients with HF and comorbid depression, we performed mixed effects logistic regression analyses to examine the cross-sectional and prospective relationships between medical and psychosocial variables and health behavior adherence, including adherence to medications, a low-sodium diet, and physician appointments.

resultsIn cross-sectional analyses, married marital status and higher physical health-related quality of life (HRQoL) were associated with greater overall adherence (compared to married, single Odds Ratio [OR] = 0.46, 95% Confidence Interval [CI] = 0.26-0.80; other OR = 0.60, CI = 0.38-0.94; p = .012. Physical HRQoL OR = 1.02, CI = 1.00-1.04, p = .047). Prospectively, greater levels of social support were associated with improved overall adherence one year later (OR = 1.04, 95% CI = 1.00-1.08, p = .037). Social support, HF symptom severity, race and ethnicity, and age were predictors of specific types of adherence. Neither depression nor optimism was significantly associated with adherence outcomes.

conclusionsThese results provide important preliminary information about risk factors for poor adherence in patients with both HF and depression, which could, in turn, contribute to the development of interventions to promote adherence in this high-risk population.

trial registrationhttps://clinicaltrials.gov/ct2/show/NCT02044211 ; registered 1/21/2014.

Indexed as

ComorbidityDepressionHealth BehaviorHeart FailureQuality of LifeAgedCross-Sectional StudiesDrug MonitoringFemaleHumansMaleMarital StatusMedication AdherenceMiddle AgedPatient ComplianceProspective StudiesAdherenceDepressionHealth behaviorHeart failure

Identifiers

PMID38835104
PMCPMC11151478

What Socratic holds

Textmetadata
LicenceCC BY
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Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.