Evidence mapPaperPMID 38835772Full record

ReviewFrontiers in immunology2024

Efferocytosis in dendritic cells: an overlooked immunoregulatory process.

Yanyan Ma, Tangxing Jiang, Xun Zhu, Yizhou Xu, Ke Wan, Tingxuan Zhang, Miaorong Xie

Abstract readReview
In one paragraph

Review in Frontiers in immunology, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 15 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
15citing papers in PubMed, 1 pooled it
field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

15 citing papers in PubMed, 1 synthesis or guideline pooled it.

  1. Pooled it
  2. Review
  3. Apolipoproteins L involvement in immunity.Journal of human immunity · 2026
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Yanyan MaDepartment of Emergency and Critical Care Center, Beijing Friendship Hospital, Capital Medical University, Beijing, China.
Tangxing JiangDepartment of Emergency Medicine, Qilu Hospital of Shandong University, Jinan, China.
Xun ZhuDepartment of Emergency and Critical Care Center, Beijing Friendship Hospital, Capital Medical University, Beijing, China.
Yizhou XuDepartment of Emergency and Critical Care Center, Beijing Friendship Hospital, Capital Medical University, Beijing, China.
Ke WanDepartment of Emergency and Critical Care Center, Beijing Friendship Hospital, Capital Medical University, Beijing, China.
Tingxuan ZhangDepartment of Emergency and Critical Care Center, Beijing Friendship Hospital, Capital Medical University, Beijing, China.
Miaorong XieDepartment of Emergency and Critical Care Center, Beijing Friendship Hospital, Capital Medical University, Beijing, China.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Efferocytosis, the process of engulfing and removing apoptotic cells, plays an essential role in preserving tissue health and averting undue inflammation. While macrophages are primarily known for this task, dendritic cells (DCs) also play a significant role. This review delves into the unique contributions of various DC subsets to efferocytosis, highlighting the distinctions in how DCs and macrophages recognize and handle apoptotic cells. It further explores how efferocytosis influences DC maturation, thereby affecting immune tolerance. This underscores the pivotal role of DCs in orchestrating immune responses and sustaining immune equilibrium, providing new insights into their function in immune regulation.

Indexed as

Dendritic CellsMacrophagesPhagocytosisAnimalsApoptosisEfferocytosisHumansImmune Toleranceantigen cross-presentationapoptotic celldendritic cellefferocytosisimmune regulationTreg differentiation

Identifiers

PMID38835772
PMCPMC11148234

What Socratic holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.