Evidence map›Paper›PMID 38836855›Full record

ArticleJournal of proteome research2024

Altered Metabolism during the Dark Period in Drosophila Short Sleep Mutants.

Dania M Malik, Seth D Rhoades, Pinky Kain, Arjun Sengupta, Amita Sehgal, Aalim M Weljie

Abstract read
In one paragraph

Article in Journal of proteome research, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 9 papers.

0numbers the graph read from it
0cells of the map it votes in
9citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

9 citing papers in PubMed.

  1. Article
  2. Article
  3. Article
  4. Sleep regulation inFrontiers in neuroscience · 2026
    Review
  5. Article
  6. Article
  7. Sleep-dependent clearance of brain lipids by peripheral blood cells.bioRxiv : the preprint server for biology · 2025
    Article
  8. Article
  9. Article
4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

6 authors.

Dania M MalikPharmacology Graduate Group, University of Pennsylvania, Philadelphia, Pennsylvania 19104, United States.
Seth D RhoadesPharmacology Graduate Group, University of Pennsylvania, Philadelphia, Pennsylvania 19104, United States.
Pinky KainDepartment of Systems Pharmacology and Translational Therapeutics, University of Pennsylvania, Philadelphia, Pennsylvania 19104, United States.
Arjun SenguptaDepartment of Systems Pharmacology and Translational Therapeutics, University of Pennsylvania, Philadelphia, Pennsylvania 19104, United States.
Amita SehgalChronobiology and Sleep Institute, University of Pennsylvania, Philadelphia, Pennsylvania 19104, United States.
Aalim M WeljieDepartment of Systems Pharmacology and Translational Therapeutics, University of Pennsylvania, Philadelphia, Pennsylvania 19104, United States.ORCID 0000-0002-7145-4494

Funding

PREDOCTORAL TRAINING PROGRAM IN PHARMACOLOGYT32GM008076 · NIGMS · UNIVERSITY OF PENNSYLVANIA · PI BLENDY, JULIE A · 1985 to 2023
$10.8M
Balance of sleep and circadian metabolic switches in DrosophilaR01DK120757 · NIDDK · UNIVERSITY OF PENNSYLVANIA · PI SEHGAL, AMITA, WELJIE, AALIM M · 2019 to 2022
$2.1M
Howard Hughes Medical InstituteNIDDK NIH HHS R01 DK120757NIGMS NIH HHS T32 GM008076
6 · The paper itself

Abstract

Sleep is regulated via circadian mechanisms, but effects of sleep disruption on physiological rhythms, in particular metabolic cycling, remain unclear. To examine this question, we probed diurnal metabolic alterations of two

Indexed as

Circadian RhythmMutationSleepAnimalsDarknessDrosophilaDrosophila melanogasterDrosophila ProteinsMetabolomeMetabolomicsOxidative StressPhotoperiodTandem Mass SpectrometryDrosophila Proteinscircadian clockDrosophilaLCMSmetabolismmetabolitesrhythmicitysleeptracing

Identifiers

PMID38836855
PMCPMC12765229

What Socratic holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.