Evidence map›Paper›PMID 38837340›Full record

ArticleInfection and immunity2024

Caspase-8 activity mediates TNFα production and restricts

Chelsea A Osbron, Crystal Lawson, Nolan Hanna, Heather S Koehler, Alan G Goodman

Abstract read
In one paragraph

Article in Infection and immunity, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed.

  1. Review
  2. Review
  3. Article
  4. Infection and immunity · 2025
    Article
  5. Article
4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

5 authors.

Chelsea A OsbronSchool of Molecular Biosciences, College of Veterinary Medicine, Washington State University, Pullman, Washington, USA.ORCID 0000-0003-1210-9284
Crystal LawsonSchool of Molecular Biosciences, College of Veterinary Medicine, Washington State University, Pullman, Washington, USA.
Nolan HannaSchool of Molecular Biosciences, College of Veterinary Medicine, Washington State University, Pullman, Washington, USA.
Heather S KoehlerSchool of Molecular Biosciences, College of Veterinary Medicine, Washington State University, Pullman, Washington, USA.
Alan G GoodmanSchool of Molecular Biosciences, College of Veterinary Medicine, Washington State University, Pullman, Washington, USA.ORCID 0000-0001-6394-332X

Funding

Exploiting a cyclic dinucleotide-mediated immune response to reduce the burden of Coxiella burnetii infectionR01AI139051 · NIAID · WASHINGTON STATE UNIVERSITY · PI GOODMAN, ALAN GABRIEL · 2019 to 2023
$2.4M
HHS | NIH | National Institute of Allergy and Infectious Diseases (NIAID) R01AI139051NIAID NIH HHS R01 AI139051Poncin Fellowship
6 · The paper itself

Abstract

PubMed holds no abstract for this paper.

Indexed as

Caspase 8Coxiella burnetiiMacrophagesQ FeverTumor Necrosis Factor-alphaAnimalsApoptosisCell LineHumansMiceReceptor-Interacting Protein Serine-Threonine KinasesSignal TransductionTHP-1 CellsCasp8 protein, mouseCaspase 8Receptor-Interacting Protein Serine-Threonine KinasesTumor Necrosis Factor-alphaapoptosiscaspasesintracellular bacterianecroptosistumor necrosis factor

Identifiers

PMID38837340
PMCPMC11238558

What Socratic holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.