Evidence map›Paper›PMID 38838013›Full record

ArticleProceedings of the National Academy of Sciences of the United States of America2024

Innate acting memory Th1 cells modulate heterologous diseases.

Nikolas Rakebrandt, Nima Yassini, Anna Kolz, Michelle Schorer, Katharina Lambert, Eva Goljat, Anna Estrada Brull, Celine Rauld, Zsolt Balazs, Michael Krauthammer and 3 more

Abstract read
In one paragraph

Article in Proceedings of the National Academy of Sciences of the United States of America, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers.

0numbers the graph read from it
0cells of the map it votes in
8citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

8 citing papers in PubMed.

  1. Article
  2. Microorganisms · 2025
    Article
  3. Article
  4. Article
  5. Article
  6. Article
  7. Article
  8. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

13 authors.

Nikolas Rakebrandt *Institute of Experimental Immunology, University of Zurich, 8057 Zurich, Switzerland.
Nima Yassini *Institute of Experimental Immunology, University of Zurich, 8057 Zurich, Switzerland.ORCID 0000-0003-0844-1276
Anna KolzInstitute of Clinical Neuroimmunology, University Hospital, Ludwig-Maximilians-Universität München, 82152 Planegg, Germany.ORCID 0000-0002-6020-7746
Michelle SchorerInstitute of Experimental Immunology, University of Zurich, 8057 Zurich, Switzerland.
Katharina LambertInstitute of Experimental Immunology, University of Zurich, 8057 Zurich, Switzerland.ORCID 0000-0002-1998-0024
Eva GoljatDepartment of Quantitative Biomedicine, University of Zurich, 8057 Zurich, Switzerland.ORCID 0009-0009-4408-3884
Anna Estrada BrullDepartment of Quantitative Biomedicine, University of Zurich, 8057 Zurich, Switzerland.ORCID 0009-0002-2470-2974
Celine RauldNovartis Biomedical Research, 4002 Basel, Switzerland.ORCID 0009-0008-5162-3570
Zsolt BalazsDepartment of Quantitative Biomedicine, University of Zurich, 8057 Zurich, Switzerland.
Michael KrauthammerDepartment of Quantitative Biomedicine, University of Zurich, 8057 Zurich, Switzerland.
José M CarballidoNovartis Biomedical Research, 4002 Basel, Switzerland.ORCID 0000-0001-8465-0665
Anneli PetersInstitute of Clinical Neuroimmunology, University Hospital, Ludwig-Maximilians-Universität München, 82152 Planegg, Germany.
Nicole JollerInstitute of Experimental Immunology, University of Zurich, 8057 Zurich, Switzerland.ORCID 0000-0003-1996-1672

Funding

Deutsche Forschungsgemeinschaft (DFG) PE 2681/1-1Deutsche Forschungsgemeinschaft (DFG) SFB-128 Teilprojekt B08EC | ERC | HORIZON EUROPE European Research Council (ERC) 677200Swiss National Science Foundation 310030_197590Swiss National Science Foundation PP00P3_150663Swiss National Science Foundation PP00P3_181037
6 · The paper itself

Abstract

Through immune memory, infections have a lasting effect on the host. While memory cells enable accelerated and enhanced responses upon rechallenge with the same pathogen, their impact on susceptibility to unrelated diseases is unclear. We identify a subset of memory T helper 1 (Th1) cells termed innate acting memory T (T

Indexed as

Immunity, InnateImmunologic MemoryInterferon-gammaTh1 CellsAnimalsInterleukin-12Legionella pneumophilaMemory T CellsMiceMice, Inbred C57BLMultiple SclerosisInterferon-gammaInterleukin-12adaptive immunityautoimmunityinfectioninnateT helper cells

Identifiers

PMID38838013
PMCPMC11181110

What Socratic holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.