Evidence map›Paper›PMID 38845183›Full record

ArticleAging cell2024

Prediagnosis recognition of acute ischemic stroke by artificial intelligence from facial images.

Yiyang Wang, Yunyan Ye, Shengyi Shi, Kehang Mao, Haonan Zheng, Xuguang Chen, Hanting Yan, Yiming Lu, Yong Zhou, Weimin Ye and 2 more

Abstract read
In one paragraph

Article in Aging cell, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
8citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

8 citing papers in PubMed, 1 synthesis or guideline pooled it.

  1. Pooled it
  2. Article
  3. Redefining Stroke Care with Artificial Intelligence: Recent Advances.Current neurology and neuroscience reports · 2026
    Review
  4. Facial Expressions as a Nexus for Health Assessment.Bioengineering (Basel, Switzerland) · 2026
    Review
  5. Article
  6. Review
  7. Article
  8. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

12 authors.

Yiyang WangPeking-Tsinghua Center for Life Sciences, Academy for Advanced Interdisciplinary Studies, Center for Quantitative Biology (CQB), Peking University, Beijing, China.ORCID 0000-0002-3863-0767
Yunyan YeEmergency Department, Ruijin Hospital, Shanghai Jiao Tong University School of Medicine, Shanghai, China.
Shengyi ShiEmergency Department, Ruijin Hospital, Shanghai Jiao Tong University School of Medicine, Shanghai, China.
Kehang MaoPeking-Tsinghua Center for Life Sciences, Academy for Advanced Interdisciplinary Studies, Center for Quantitative Biology (CQB), Peking University, Beijing, China.
Haonan ZhengPeking-Tsinghua Center for Life Sciences, Academy for Advanced Interdisciplinary Studies, Center for Quantitative Biology (CQB), Peking University, Beijing, China.ORCID 0000-0001-7096-2019
Xuguang ChenEmergency Department, Ruijin Hospital, Shanghai Jiao Tong University School of Medicine, Shanghai, China.
Hanting YanEmergency Department, Ruijin Hospital, Shanghai Jiao Tong University School of Medicine, Shanghai, China.
Yiming LuEmergency Department, Ruijin Hospital, Shanghai Jiao Tong University School of Medicine, Shanghai, China.
Yong ZhouClinical Research Institute, Shanghai General Hospital, Shanghai Jiao Tong University School of Medicine, Shanghai, China.ORCID 0000-0001-5221-8026
Weimin YeSchool of Public Health, Fujian Medical University, Fuzhou, China.
Jing YeEmergency Department, Ruijin Hospital, Shanghai Jiao Tong University School of Medicine, Shanghai, China.ORCID 0000-0002-9471-3321
Jing-Dong J HanPeking-Tsinghua Center for Life Sciences, Academy for Advanced Interdisciplinary Studies, Center for Quantitative Biology (CQB), Peking University, Beijing, China.ORCID 0000-0002-9270-7139

Funding

Ministry of Science and Technology of the People's Republic of China 2020YFA0804000National Natural Science Foundation of China 32088101National Natural Science Foundation of China 32330017National Natural Science Foundation of China 82225018National Natural Science Foundation of China 92049302National Natural Science Foundation of China 92374207
6 · The paper itself

Abstract

Stroke is a major threat to life and health in modern society, especially in the aging population. Stroke may cause sudden death or severe sequela-like hemiplegia. Although computed tomography (CT) and magnetic resonance imaging (MRI) are standard diagnosis methods, and artificial intelligence models have been built based on these images, shortage in medical resources and the time and cost of CT/MRI imaging hamper fast detection, thus increasing the severity of stroke. Here, we developed a convolutional neural network model by integrating four networks, Xception, ResNet50, VGG19, and EfficientNetb1, to recognize stroke based on 2D facial images with a cross-validation area under curve (AUC) of 0.91 within the training set of 185 acute ischemic stroke patients and 551 age- and sex-matched controls, and AUC of 0.82 in an independent data set regardless of age and sex. The model computed stroke probability was quantitatively associated with facial features, various clinical parameters of blood clotting indicators and leukocyte counts, and, more importantly, stroke incidence in the near future. Our real-time facial image artificial intelligence model can be used to rapidly screen and prediagnose stroke before CT scanning, thus meeting the urgent need in emergency clinics, potentially translatable to routine monitoring.

Indexed as

Artificial IntelligenceFaceIschemic StrokeAgedFemaleHumansMaleMiddle AgedNeural Networks, ComputerStrokeagingdiagnosis modelfacial imagesstroke

Identifiers

PMID38845183
PMCPMC11320352

What Socratic holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.