ArticleAdvanced science (Weinheim, Baden-Wurttemberg, Germany)2024
GhMPK9-GhRAF39_1-GhWRKY40a Regulates the GhERF1b- and GhABF2-Mediated Pathways to Increase Cotton Disease Resistance.
Article in Advanced science (Weinheim, Baden-Wurttemberg, Germany), 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 21 papers.
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Who cites it
21 citing papers in PubMed.
- Plant Phosphatidylinositol Signalling Network in Cotton Resistance to Verticillium Wilt.Plant, cell & environment · 2026Review
- Article
- The Regulatory Army of Plant Defense: Transcription Factors in the War for Plant Immunity.International journal of molecular sciences · 2026Review
- Decoding MAPK cascades in plant immunity: Activation, regulation, integration, and pathogen manipulation.Journal of integrative plant biology · 2026Review
- The GhWRKY70-International journal of molecular sciences · 2026Article
- Infection-responsive alternative splicing of GhZDS is associated with Verticillium wilt resistance in cotton.BMC plant biology · 2026Article
- WRKY Transcription Factors: Integral Regulators of Defence Responses to Biotic Stress in Crops.Plant biotechnology journal · 2026Review
- Article
- MT@SiOPlant biotechnology journal · 2026Article
- Article
- GbWAKL20 Phosphorylates GbNFYB8 to Modulate Verticillium Wilt Resistance in Cotton.Advanced science (Weinheim, Baden-Wurttemberg, Germany) · 2026Article
- Review
- Genome-Wide Identification Analysis of theGenes · 2025Article
- A Cotton Laccase Confers Disease Resistance Against Verticillium dahliae by Promoting Cell Wall Lignification.Molecular plant pathology · 2025Article
- The Apple Mitogen-Activated Protein KinaseInternational journal of molecular sciences · 2025Article
- Integrative identification of key genes governingFrontiers in plant science · 2025Article
- Subfamily C7 Raf-like kinases MRK1, RAF26, and RAF39 regulate immune homeostasis and stomatal opening in Arabidopsis thaliana.The New phytologist · 2024Article
- Dual Transcriptome Analysis Reveals the Changes in Gene Expression in Both Cotton andJournal of fungi (Basel, Switzerland) · 2024Article
- WRKY Transcription Factors in Response to Metal Stress in Plants: A Review.International journal of molecular sciences · 2024Review
- GhMPK9-GhRAF39_1-GhWRKY40a Regulates the GhERF1b- and GhABF2-Mediated Pathways to Increase Cotton Disease Resistance.Advanced science (Weinheim, Baden-Wurttemberg, Germany) · 2024Article
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8 authors.
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Abstract
Mitogen-activated protein kinase (MAPK) cascade is the center of plant signal transduction system that amplify immune signals into cellular responses by phosphorylating diverse substrates. The MAPK cascade consisting of MAPK kinase kinases (MAPKKKs), MAPK kinases (MAPKKs), and MAPKs is well characterized in plants, in which Raf-like kinases are generally regarded as MAPKKKs. However, it is rarely reported that Raf-like MAPKKKs function as middle regulators to link MAPK and its downstream transcription factors in plant immunity. Verticillium wilt, caused by the soil-borne vascular fungus Verticillium dahliae, is a serious disease in many plants, including cotton. The previous studies showed that GhMPK9 (a MAPK) is involved in the response to Verticillium wilt. Here, the Raf-like kinase GhRAF39_1 is reported as helper regulates the phosphorylation of WRKY transcription factor GhWRKY40a by GhMPK9. The phosphorylated GhWRKY40a can further activate the transcription of GhERF1b to up-regulate defense-related genes while inhibit the transcription of GhABF2 to regulate the stomatal opening, thus improving the resistance to Verticillium wilt in cotton. This study reveals a new signaling module of GhMPK9-GhRAF39_1-GhWRKY40a to regulate GhERF1b- and GhABF2-mediated defense responses, which triggers plant defense against Verticillium wilt.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.