Evidence mapPaperPMID 38846261Full record

ReviewEthnicity & disease2023

Commentary on Metabolic Health Disparities Affecting the Rio Grande Valley Mexican American Population: Seeking Answers Using Animal Models.

Juan Carlos Lopez-Alvarenga, Cordelia Rasa, Jameela Banu, Shizue Mito, Alberto O Chavez, Sara M Reyna

Abstract readReview
In one paragraph

Review in Ethnicity & disease, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Juan Carlos Lopez-AlvarengaPopulation Health and Biostatistics, School of Medicine, University of Texas Rio Grande Valley, Edinburg, TX.
Cordelia RasaDepartment of Laboratory Animal Resources, University of Texas Rio Grande Valley, Edinburg, TX.
Jameela BanuDepartment of Health and Biomedical Sciences, University of Texas Rio Grande Valley, Edinburg, TX.
Shizue MitoDepartment of Medical Education, School of Medicine, University of Texas Rio Grande Valley, Edinburg, TX.
Alberto O ChavezDivision of Diabetes, Department of Medicine, University of Texas Health Science Center at San Antonio, San Antonio, TX.
Sara M ReynaDepartment of Human Genetics, School of Medicine, University of Texas Rio Grande Valley, Edinburg, TX.

Funding

NIGMS NIH HHS SC2 GM127272
6 · The paper itself

Abstract

Mexican Americans living in the Rio Grande Valley (RGV) have a high prevalence of type 2 diabetes (T2D). The US-Mexico border frontier has a unique blended culture of American lifestyle and Mexican traditions. Some examples of the cultural traditions are the food and the use of herbal medicine, but these traditions are in danger of disappearing after a very short number of generations living in the United States. This article describes the use of animal models under experimental conditions to solve practical questions (etiology or treatment). We performed studies with murine (ie, mouse and rat) models to elucidate the characteristics of medicinal plants that modulate glucose metabolism and inflammation and protect from bone loss, complications related to T2D. The University of Texas Rio Grande Valley researchers also have collaborated with the University of Texas Health Science Center at San Antonio researchers in performing studies in nonhuman primates (NHP) (ie, baboon) to understand the effect of T2D and diets on organs and tissues. With the new knowledge gained from the use of animal models (murine and NHP), new therapies are discovered for the prevention and treatment of T2D and its related complications, such as bone loss and nonalcoholic fatty liver disease, all of which the Mexican American and other human populations are at high risk of developing.

Indexed as

Diabetes Mellitus, Type 2Disease Models, AnimalMexican AmericansAnimalsHealth Status DisparitiesHumansMexicoMiceRatsTexasAnimal ModelHealth DisparitiesMexican AmericanRio Grande ValleyType 2 Diabetes

Identifiers

PMID38846261
PMCPMC11152149

What Socratic holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.