Evidence map›Paper›PMID 38847940›Full record

ReviewCell biochemistry and biophysics2024

Intermittent Fasting Regulates Metabolic Homeostasis and Improves Cardiovascular Health.

Rawan Diab, Lina Dimachkie, Omar Zein, Ali Dakroub, Ali H Eid

Abstract readReview
In one paragraph

Review in Cell biochemistry and biophysics, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 17 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
17citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

17 citing papers in PubMed, 1 synthesis or guideline pooled it.

  1. Pooled it
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  11. Circadian nutrition and obesity: timing as a nutritional strategy.Journal of health, population, and nutrition · 2025
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Rawan Diab *Faculty of Medicine, American University of Beirut Medical Center, Beirut, Lebanon.
Lina Dimachkie *Faculty of Medicine, American University of Beirut Medical Center, Beirut, Lebanon.
Omar Zein *Faculty of Medicine, American University of Beirut Medical Center, Beirut, Lebanon.
Ali DakroubSt. Francis Hospital and Heart Center, Roslyn, NY, USA.
Ali H EidDepartment of Basic Medical Sciences, College of Medicine, Qatar University, QU Health, Doha, Qatar. ali.eid@qu.edu.qa.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Obesity is a leading cause of morbidity and mortality globally. While the prevalence of obesity has been increasing, the incidence of its related complications including dyslipidemia and cardiovascular disease (CVD) has also been rising. Recent research has focused on modalities aimed at reducing obesity. Several modalities have been suggested including behavioral and dietary changes, medications, and bariatric surgery. These modalities differ in their effectiveness and invasiveness, with dietary changes gaining more interest due to their minimal risks compared to other modalities. Specifically, intermittent fasting (IF) has been gaining interest in the past decade. IF is characterized by cycles of alternating fasting and eating windows, with several different forms practiced. IF has been shown to reduce weight and alleviate obesity-related complications. Our review of clinical and experimental studies explores the effects of IF on the lipid profile, white adipose tissue (WAT) dynamics, and the gut microbiome. Notably, IF corrects dyslipidemia, reduces WAT accumulation, and decreases inflammation, which reduces CVD and obesity. This comprehensive analysis details the protective metabolic role of IF, advocating for its integration into public health practices.

Indexed as

Cardiovascular DiseasesFastingGastrointestinal MicrobiomeHomeostasisAdipose Tissue, WhiteAnimalsDyslipidemiasHumansIntermittent FastingObesityAdipose tissueCaloric restrictionCardiovascular diseaseDyslipidemiaMetabolic disease

Identifiers

PMID38847940
PMCPMC11445340

What Socratic holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.