Evidence map›Paper›PMID 38850338›Full record

ReviewWorld journal of microbiology & biotechnology2024

Multidrug resistance profile in Lactobacillus delbrueckii: a food industry species with probiotic properties.

Ludmila Silva Quaresma, Rhayane Cristina Viegas Santos, Gabriel Camargos Gomes, Monique Ferrary Américo, Gabriela Munis Campos, Juliana Guimarães Laguna, Fernanda Alvarenga Lima Barroso, Vasco Azevedo, Luís Cláudio Lima de Jesus

Abstract readReview
PubMed Publisher
In one paragraph

Review in World journal of microbiology & biotechnology, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed.

  1. Review
  2. Article
  3. The Invisible Threat of Antibiotic Resistance in Food.Antibiotics (Basel, Switzerland) · 2025
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors.

Ludmila Silva Quaresma *Department of Genetics, Ecology, and Evolution, Federal University of Minas Gerais, Belo Horizonte, 31270-901, Brazil.
Rhayane Cristina Viegas Santos *Department of Genetics, Ecology, and Evolution, Federal University of Minas Gerais, Belo Horizonte, 31270-901, Brazil.
Gabriel Camargos GomesDepartment of Genetics, Ecology, and Evolution, Federal University of Minas Gerais, Belo Horizonte, 31270-901, Brazil.
Monique Ferrary AméricoDepartment of Genetics, Ecology, and Evolution, Federal University of Minas Gerais, Belo Horizonte, 31270-901, Brazil.
Gabriela Munis CamposDepartment of Genetics, Ecology, and Evolution, Federal University of Minas Gerais, Belo Horizonte, 31270-901, Brazil.
Juliana Guimarães LagunaDepartment of Genetics, Ecology, and Evolution, Federal University of Minas Gerais, Belo Horizonte, 31270-901, Brazil.
Fernanda Alvarenga Lima BarrosoDepartment of Genetics, Ecology, and Evolution, Federal University of Minas Gerais, Belo Horizonte, 31270-901, Brazil.
Vasco Azevedo *Department of Genetics, Ecology, and Evolution, Federal University of Minas Gerais, Belo Horizonte, 31270-901, Brazil. vasco@icb.ufmg.br.
Luís Cláudio Lima de Jesus *Department of Genetics, Ecology, and Evolution, Federal University of Minas Gerais, Belo Horizonte, 31270-901, Brazil. luiislimma@gmail.com.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Lactobacillus delbrueckii, a widely used lactic acid bacterium in the food industry, has been studied for its probiotic properties and reservoir of antibiotic-resistant genes, raising safety concerns for probiotic formulations and fermented products. This review consolidates findings from 60 articles published between 2012 and 2023, focusing on the global antibiotic resistance profile and associated genetic factors in L. delbrueckii strains. Resistance to aminoglycosides, particularly streptomycin, kanamycin, and gentamicin, as well as resistance to glycopeptides (vancomycin), fluoroquinolones (ciprofloxacin), and tetracyclines was predominant. Notably, although resistance genes have been identified, they have not been linked to mobile genetic elements, reducing the risk of dissemination. However, a significant limitation is the insufficient exploration of responsible genes or mobile elements in 80% of studies, hindering safety assessments. Additionally, most articles originated from Asian and Middle Eastern countries, with strains often isolated from fermented dairy foods. Therefore, these findings underscore the necessity for comprehensive analyses of new strains of L. delbrueckii for potential industrial and biotherapeutic applications and in combating the rise of antibiotic-resistant pathogens.

Indexed as

Anti-Bacterial AgentsLactobacillus delbrueckiiProbioticsDrug Resistance, Multiple, BacterialFermented FoodsFood IndustryFood MicrobiologyAnti-Bacterial AgentsAntimicrobial resistanceFermented foodsFood SafetyGut resistomeMobilome

Identifiers

PMID38850338

What Socratic holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.