Evidence map›Paper›PMID 38853095›Full record

ArticleDisability and health journal2024

Elevated blood pressure in children with cerebral palsy and its relationship with adiposity and physical activity.

Junsoo Lee, Trevor Batson, Kevin K McCully, Ye Shen, Christopher M Modlesky

Abstract read
In one paragraph

Article in Disability and health journal, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

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1 · What the graph read from it

What it found

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2 · The registry

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3 · Its place in the literature

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4 · The record

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5 · Who and what money

Authors and funding

5 authors.

Junsoo LeeDepartment of Kinesiology, University of Georgia, Athens, GA, USA.
Trevor BatsonDepartment of Kinesiology, University of Georgia, Athens, GA, USA.
Kevin K McCullyDepartment of Kinesiology, University of Georgia, Athens, GA, USA.
Ye ShenDepartment of Epidemiology and Biostatistics, University of Georgia, Athens, GA, USA.
Christopher M ModleskyDepartment of Kinesiology, University of Georgia, Athens, GA, USA. Electronic address: christopher.modlesky@uga.edu.

Funding

Effect of vibration on muscle properties, physical activity and balance in children with cerebral palsyR01HD090126 · NICHD · UNIVERSITY OF GEORGIA · PI MODLESKY, CHRISTOPHER M · 2017 to 2022
$3.0M
NICHD NIH HHS R01 HD090126
6 · The paper itself

Abstract

backgroundThere is a high prevalance of hypertension in adults with with cerebral palsy (CP). However, less is known about blood pressure in children with CP.

objectiveThe aim was to determine if blood pressure is elevated in children with CP and whether it is related to adiposity and physical activity.

methodsThirty children with spastic CP (5-11 y) and 30 age-, sex-, and race-matched typically developing control children were studied. Resting systolic blood pressure (SBP), diastolic blood pressure (DBP), and heart rate were measured, and mean arterial pressure (MAP) was calculated. Visceral fat mass and total body fat mass index (FMI) were determined using dual-energy X-ray absorptiometry. Physical activity was assessed using accelerometer-based monitors.

resultsChildren with CP had higher DBP and heart rate than controls (p < 0.05). DBP percentile and MAP were also higher in children with CP when BMI was statistically controlled. Children with CP and elevated blood pressure or hypertension (n = 8) had 56% more visceral fat mass than children with CP and normal blood pressure (n = 22; p < 0.05). In the groups combined, blood pressure was directly related to visceral fat mass and FMI, and inversely related to physical activity (p < 0.05). However, in children with CP alone, only visceral fat mass was related to blood pressure (p < 0.05).

conclusionsChildren with CP have higher resting blood pressure than typically developing children. The higher blood pressure is related to higher visceral adiposity. Careful blood pressure screening should start during childhood in individuals with CP.

Indexed as

Absorptiometry, PhotonAdiposityBlood PressureCerebral PalsyExerciseHeart RateHypertensionBody Mass IndexCase-Control StudiesChildChild, PreschoolFemaleHumansIntra-Abdominal FatMalePersons with DisabilitiesBody compositionCerebral palsyHypertensionTotal body fatVisceral fat

Identifiers

PMID38853095
PMCPMC12696650

What Socratic holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.