Evidence map›Paper›PMID 38854131›Full record

ArticleResearch square2024

A roadmap to human hippocampal neurogenesis in adulthood, aging and AD.

Orly Lazarov, Ahmed Disouky, Mark Sanborn, Mostafa Mostafa, K Sabitha, Aimee Schantz, Namhee Kim, Szymon Pawlowski, William Honer, David Bennett and 4 more

Abstract readPreprint
In one paragraph

Article in Research square, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

14 authors.

Orly LazarovThe University of Illinois at Chicago.ORCID 0000-0002-5887-948X
Ahmed DisoukyThe University of Illinois at Chicago.
Mark SanbornUniversity of Illinois at Chicago.
Mostafa MostafaThe University of Illinois at Chicago.
K SabithaThe University of Illinois at Chicago.
Aimee SchantzUniversity of Washington.ORCID 0009-0006-2634-4970
Namhee KimRush University.
Szymon PawlowskiThe University of Illinois at Chicago.
William HonerThe University of British Columbia.
David BennettRush University Medical Center.
Yi ZhouInstitute of Neuroscience, Chinese Academy of Sciences.ORCID 0000-0001-6500-8554
C KeeneUniversity of Washington.ORCID 0000-0002-5291-1469
Mark Maienschein-ClineUniversity of Illinois at Chicago.
Jalees RehmanUniversity of Illinois at Chicago.ORCID 0000-0002-2787-9292

Funding

Functionally guided adult whole brain cell atlas in human and NHPUM1MH130981 · NIMH · ALLEN INSTITUTE · PI Ed Lein, Hongkui Zeng · 2022 to 2026
$91.9M
Translational pharmacoepidemiology: neuroprotection and neurotoxicity of antihypertensives and strong anticholinergicsU19AG066567 · NIA · KAISER FOUNDATION RESEARCH INSTITUTE · PI Linda Kathleen McEvoy · 2021 to 2026
$80.4M
Strengthening Stakeholder Engagement in Human Research Protections.UL1TR002003 · NCATS · UNIVERSITY OF ILLINOIS AT CHICAGO · PI KARNIK, NIRANJAN SUBHASH, MERMELSTEIN, ROBIN J. · 2016 to 2024
$33.7M
University of Washington Alzheimer's Disease Research CenterP30AG066509 · NIA · UNIVERSITY OF WASHINGTON · PI Amanda D. Boyd · 2020 to 2026
$29.0M
Data Coordinating CoreU54NS115322 · NINDS · UNIVERSITY OF PENNSYLVANIA · PI SMITH, DOUGLAS HAMILTON · 2019 to 2023
$9.2M
Interdisciplinary Research Network on Biologically Active Tau Aggregate Polymorphs from Alzheimer's Disease and Related DementiasU24AG072458 · NIA · UNIVERSITY OF TEXAS MED BR GALVESTON · PI EISENBERG, DAVID, KAYED, RAKEZ · 2021 to 2025
$7.8M
The role of PS1 in regulation of adult neurogenesis in the intact and Alzheimer?sR01AG033570 · NIA · UNIVERSITY OF ILLINOIS AT CHICAGO · PI Orly Lazarov · 2009 to 2026
$5.6M
Hippocampal neurogenesis in cognitive function and dysfunction in Alzheimer's disease.R01AG076940 · NIA · UNIVERSITY OF ILLINOIS AT CHICAGO · PI Orly Lazarov · 2022 to 2026
$3.7M
Plasticity circuits in Alzheimer s diseaseRF1AG033570 · NIA · UNIVERSITY OF ILLINOIS AT CHICAGO · PI LAZAROV, ORLY · 2020 to 2021
$2.9M
Mechanisms underlying sporadic Alzheimer's diseaseR01AG060238 · NIA · UNIVERSITY OF ILLINOIS AT CHICAGO · PI LAZAROV, ORLY · 2018 to 2022
$2.4M
Training program in the biology and translational research on Alzheimer's diseaseand related dementiasT32AG057468 · NIA · UNIVERSITY OF ILLINOIS AT CHICAGO · PI Stephanie M Cologna, Orly Lazarov · 2017 to 2026
$2.3M
Acceleration of AD Phenotypes in Asymptomatic Mouse ModelsR01AG062251 · NIA · UNIVERSITY OF ILLINOIS AT CHICAGO · PI LAZAROV, ORLY · 2018 to 2022
$2.2M
NCATS NIH HHS UL1 TR002003NHLBI NIH HHS T32 HL139439NIA NIH HHS F31 AG090005NIA NIH HHS P30 AG066509NIA NIH HHS R01 AG033570NIA NIH HHS R01 AG060238NIA NIH HHS R01 AG062251NIA NIH HHS R01 AG076940NIA NIH HHS R01 AG079002NIA NIH HHS R21 AG061628NIA NIH HHS RF1 AG033570NIA NIH HHS RF1 AG079002NIA NIH HHS T32 AG057468NIA NIH HHS U19 AG066567NIA NIH HHS U24 AG072458NIMH NIH HHS UM1 MH130981NINDS NIH HHS U54 NS115322
6 · The paper itself

Abstract

In the rodent, hippocampal neurogenesis plays critical roles in learning and memory

Identifiers

PMID38854131
PMCPMC11160907

What Socratic holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.