Evidence map›Paper›PMID 38855694›Full record

ArticleBiomedical optics express2024

Visualization of carious lesions with polarized and depolarized light microscopy.

Julia Grundmann, Jonas Golde, Svea Steuer, Florian Tetschke, Lars Kirsten, Julia Walther, Edmund Koch, Christian Hannig

Abstract read
In one paragraph

Article in Biomedical optics express, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers.

0numbers the graph read from it
0cells of the map it votes in
8citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

8 citing papers in PubMed.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Julia GrundmannTU Dresden, Faculty of Medicine Carl Gustav Carus, Policlinic of Operative Dentistry, Periodontology and Pediatric Dentistry, Fetscherstrasse 74, 01307 Dresden, Germany.
Jonas GoldeTU Dresden, Faculty of Medicine Carl Gustav Carus, Medical Physics and Biomedical Engineering, Fetscherstrasse 74, 01307 Dresden, Germany.ORCID https://orcid.org/0000-0002-8160-3000
Svea SteuerTU Dresden, Faculty of Medicine Carl Gustav Carus, Anesthesiology and Intensive Care Medicine, Clinical Sensoring and Monitoring, Fetscherstrasse 74, 01307 Dresden, Germany.ORCID https://orcid.org/0009-0002-1419-8698
Florian TetschkeTU Dresden, Faculty of Medicine Carl Gustav Carus, Policlinic of Operative Dentistry, Periodontology and Pediatric Dentistry, Fetscherstrasse 74, 01307 Dresden, Germany.
Lars KirstenTU Dresden, Faculty of Medicine Carl Gustav Carus, Medical Physics and Biomedical Engineering, Fetscherstrasse 74, 01307 Dresden, Germany.
Julia WaltherTU Dresden, Faculty of Medicine Carl Gustav Carus, Medical Physics and Biomedical Engineering, Fetscherstrasse 74, 01307 Dresden, Germany.
Edmund KochTU Dresden, Faculty of Medicine Carl Gustav Carus, Anesthesiology and Intensive Care Medicine, Clinical Sensoring and Monitoring, Fetscherstrasse 74, 01307 Dresden, Germany.ORCID https://orcid.org/0000-0003-0554-2178
Christian HannigTU Dresden, Faculty of Medicine Carl Gustav Carus, Policlinic of Operative Dentistry, Periodontology and Pediatric Dentistry, Fetscherstrasse 74, 01307 Dresden, Germany.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Polarized light microscopy (PLM) is an established method in dental histology for investigating the ultrastructure and carious process of teeth. This study introduces a novel approach for measuring the degree of polarization (DOP) in a modified PLM setup and uses the DOP to assess the changes of the optical properties of enamel and dentin due to caries. The validation is provided by a comparison with complementary imaging methods, i.e. standard PLM and µCT. The results show that demineralization is reliably displayed by the DOP in accordance with the common imaging methods, and that this quantitative analysis of depolarization allows the characterization of the different pathohistological zones of caries.

Identifiers

PMID38855694
PMCPMC11161379

What Socratic holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.