Evidence map›Paper›PMID 38858645›Full record

ArticleBMC medical imaging2024

Alterations in structural integrity of superior longitudinal fasciculus III associated with cognitive performance in cerebral small vessel disease.

Yifan Wang, Tianyao Wang, Zekuan Yu, Junjie Wang, Fang Liu, Mengwen Ye, Xianjin Fang, Yinhong Liu, Jun Liu

Abstract read
In one paragraph

Article in BMC medical imaging, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Article
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors.

Yifan Wang *Department of Radiology, Eye& ENT Hospital of Shanghai Medical School, Fudan University, Shanghai, China.ORCID http://orcid.org/0000-0002-7546-2096
Tianyao Wang *Department of Radiology, Renji Hospital, Shanghai Jiao Tong University School of Medicine, Shanghai, China.
Zekuan YuAcademy for Engineering and Technology, Fudan University, Shanghai, 200433, China.
Junjie WangDepartment of Neurosurgery, Beijing Hospital, National Center of Gerontology, Beijing, China.
Fang LiuInstitute of Geriatric Medicine, Chinese Academy of Medical Sciences, Beijing, China.
Mengwen YeAcademy for Engineering and Technology, Fudan University, Shanghai, 200433, China.
Xianjin FangAnhui University of Science and Technology, Anhui, China.
Yinhong LiuInstitute of Geriatric Medicine, Chinese Academy of Medical Sciences, Beijing, China. liuyh302@126.com.
Jun LiuDepartment of Radiology, Tongren Hospital, Shanghai Jiao Tong University School of Medicine, 1111 XianXia Road, Shanghai, 200050, China. 1554165538@qq.com.ORCID http://orcid.org/0000-0002-2400-7683

Funding

Anhui University of Science and Technology NO. EK20201003National Natural Science Foundation of China 82103964
6 · The paper itself

Abstract

backgroundThis study aimed to investigate the alterations in structural integrity of superior longitudinal fasciculus subcomponents with increasing white matter hyperintensity severity as well as the relationship to cognitive performance in cerebral small vessel disease.

methods110 cerebral small vessel disease study participants with white matter hyperintensities were recruited. According to Fazekas grade scale, white matter hyperintensities of each subject were graded. All subjects were divided into two groups. The probabilistic fiber tracking method was used for analyzing microstructure characteristics of superior longitudinal fasciculus subcomponents.

resultsProbabilistic fiber tracking results showed that mean diffusion, radial diffusion, and axial diffusion values of the left arcuate fasciculus as well as the mean diffusion value of the right arcuate fasciculus and left superior longitudinal fasciculus III in high white matter hyperintensities rating group were significantly higher than those in low white matter hyperintensities rating group (p < 0.05). The mean diffusion value of the left superior longitudinal fasciculus III was negatively related to the Montreal Cognitive Assessment score of study participants (p < 0.05).

conclusionsThe structural integrity injury of bilateral arcuate fasciculus and left superior longitudinal fasciculus III is more severe with the aggravation of white matter hyperintensities. The structural integrity injury of the left superior longitudinal fasciculus III correlates to cognitive impairment in cerebral small vessel disease.

Indexed as

Cerebral Small Vessel DiseasesDiffusion Tensor ImagingWhite MatterAgedCognitionCognitive DysfunctionFemaleHumansMaleMiddle AgedCerebral small vessel diseaseCognitionDiffusion tensor imagingSuperior longitudinal fasciculusWhite matter hyperintensities

Identifiers

PMID38858645
PMCPMC11165890

What Socratic holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.