Evidence mapPaperPMID 38858730Full record

ArticleBMC nutrition2024

Double malnutrition and associated factors in a middle-aged and older, rural South African population.

Faheem Seedat, Stephen M Tollman, Wayne Twine, Anne R Cappola, Alisha N Wade

Abstract read
In one paragraph

Article in BMC nutrition, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed.

  1. Article
  2. Article
  3. Defining double burden of malnutrition across individual, household and population level: A narrative review.Nutrition & dietetics : the journal of the Dietitians Association of Australia · 2026
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Faheem SeedatDivision of Endocrinology and Metabolism, Helen Joseph Hospital, University of the Witwatersrand, Johannesburg, South Africa.
Stephen M TollmanMRC/Wits Rural Public Health and Health Transitions Research Unit, School of Public Health, University of the Witwatersrand, Johannesburg, South Africa.
Wayne TwineSchool of Animal, Plant and Environmental Sciences, University of the Witwatersrand, Johannesburg, South Africa.
Anne R CappolaDivision of Endocrinology, Diabetes and Metabolism, Perelman School of Medicine, University of Pennsylvania, Philadelphia, PA, USA.
Alisha N WadeMRC/Wits Rural Public Health and Health Transitions Research Unit, School of Public Health, University of the Witwatersrand, Johannesburg, South Africa. alisha.wade@wits.ac.za.

Funding

SOCIAL AND ECONOMIC PREDICTORS OF PHYSICAL AND COGNITIVE FUNCTIONP01AG041710 · NIA · HARVARD UNIVERSITY D/B/A HARVARD SCHOOL OF PUBLIC HEALTH · PI LISA F BERKMAN, THOMAS A GAZIANO · 2013 to 2026
$37.3M
Shared Core: Biobanking, Bioinformatics and Data ManagementU54HG006938 · NHGRI · WITS HEALTH CONSORTIUM (PTY), LTD · PI RAMSAY, MICHELE MICHELE · 2012 to 2022
$12.2M
Midcareer Investigator Award in Patient-Oriented Research in AgingK24AG042765 · NIA · UNIVERSITY OF PENNSYLVANIA · PI CAPPOLA, ANNE R · 2013 to 2024
$1.7M
Endocrine and metabolic diseases in rural South Africa-establishing burden and improving detectionK43TW010698 · FIC · WITS HEALTH CONSORTIUM (PTY), LTD · PI WADE, ALISHA NICOLE · 2017 to 2021
$581k
RISKY BUSINESS--LIVING IN A CHEMICAL WORLDR25ES006938 · NIEHS · UNIVERSITY OF WASHINGTON · PI EATON, DAVID L · 1994 to 1997
African Partnership for Chronic Disease Research n/aDepartment of Science and Innovation, South Africa DST/CON 0056/2014Eunice Kennedy Shriver National Institute of Child Health and Human Development U54HG006938FIC NIH HHS K43 TW010698FIC NIH HHS K43TW010698NHGRI NIH HHS U54HG006938NIA NIH HHS K24AG042765NIA NIH HHS P01 AG041710NIDDK NIH HHS U54HG006938NIEHS NIH HHS U54HG006938NIH Office of the Director U54HG006938Office of AIDS Research U54HG006938
6 · The paper itself

Abstract

introductionDouble malnutrition (co-existing overnutrition and undernutrition) is increasingly prevalent in sub-Saharan Africa due to rapid epidemiological and nutritional transitions. In this region, studies of double malnutrition have largely been conducted at country and household level, with individual-level studies primarily limited to children and women of reproductive age. We investigated the prevalence and determinants of individual-level double malnutrition in middle-aged and older adults who constitute an increasing proportion of the sub-Saharan African population.

methods250 individuals aged 40-70 years (50% women) and resident in the Agincourt Health and socio-Demographic Surveillance System in rural Mpumalanga province, South Africa, were randomly selected. Double malnutrition was defined as overweight/obesity and anaemia only, overweight/obesity and iodine insufficiency, or overweight/obesity and any micronutrient deficiency (anaemia and/or iodine insufficiency). The Chi-squared goodness of fit test was used to compare the expected and observed numbers of individuals with the type of double malnutrition. Logistic regression was used to investigate determinants of each type of double malnutrition.

resultsDouble malnutrition was present in 22-36% of participants, depending on the definition used. All types of double malnutrition were more common in women than in men (overweight/obesity and anaemia: 34% vs. 10.2%, p < 0.01; overweight/obesity and iodine insufficiency: 32% vs. 12.2%, p < 0.01 and overweight/obesity and any micronutrient deficiency: 50.5% vs. 20.4%, p < 0.01). There were no differences between the overall expected and observed numbers of individuals with combinations of overweight and micronutrient deficiencies [overweight/obesity and anaemia (p = 0.28), overweight/obesity and iodine insufficiency (p = 0.27) or overweight/obesity and any micronutrient deficiency (p = 0.99)]. In models adjusted for socio-demographic factors, HIV and antiretroviral drug status, and food security or dietary diversity, men were 84-85% less likely than women to have overweight/obesity and anaemia, 65% less likely to have overweight/obesity and iodine insufficiency and 74% less likely to have overweight/obesity and any micronutrient deficiency.

conclusionsIndividual-level double malnutrition is prevalent in middle-aged and older adults in a rural sub-Saharan African community. Interventions to improve nutrition in similar settings should target individuals throughout the life course and a focus on women may be warranted.

Indexed as

AnaemiaIodine deficiencyMalnutritionObesitySouth Africa

Identifiers

PMID38858730
PMCPMC11163772

What Socratic holds

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.