Evidence map›Paper›PMID 38859869›Full record

ArticleAmerican journal of cancer research2024

Tannic acids and proanthocyanidins in tea inhibit SARS-CoV-2 variants infection.

Chung-Yu Chen, Wei-Jan Wang, Chen-Shiou Wu, Shao-Chun Wang, Wei-Chao Chang, Mien-Chie Hung

Abstract read
In one paragraph

Article in American journal of cancer research, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed.

  1. Review
  2. Review
  3. A Comprehensive Review of Phenolic Compounds in Horticultural Plants.International journal of molecular sciences · 2025
    Review
  4. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Chung-Yu ChenResearch Center for Cancer Biology, China Medical University Taichung 406040, Taiwan.
Wei-Jan WangResearch Center for Cancer Biology, China Medical University Taichung 406040, Taiwan.
Chen-Shiou WuResearch Center for Cancer Biology, China Medical University Taichung 406040, Taiwan.
Shao-Chun WangResearch Center for Cancer Biology, China Medical University Taichung 406040, Taiwan.
Wei-Chao ChangCenter for Molecular Medicine, China Medical University Hospital, China Medical University Taichung 406040, Taiwan.
Mien-Chie HungResearch Center for Cancer Biology, China Medical University Taichung 406040, Taiwan.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The COVID-19 pandemic has caused hundreds million cases and millions death as well as continues to infect human life in the world since late of 2019. The breakthrough infection caused from mutation of SARS-CoV-2 is rising even the vaccinated population has been increasing. Currently, the severe threat posed by SARS-CoV-2 has been alleviated worldwide, and the situation has transitioned to coexisting with the virus. The dietary food with antiviral activities may improve to prevent virus infection for living with COVID-19 pandemic. Teas containing enriched phenolic ingredients such as tannins have been reported to be antitumor agents as well as be good inhibitors for coronavirus. This study developed a highly sensitive and selective ultra-high performance liquid chromatography-high resolution mass spectrometric method for quantification of tannic acids, a hydrolysable tannin, and proanthocyanidins, a condense tannin, in teas with different levels of fermentation. The in vitro pseudoviral particles (Vpp) infection assay was used to evaluate the inhibition activities of various teas. The results of current research demonstrate that the tannins in teas are effective inhibitors against infection of SARS-CoV-2 and its variants.

Indexed as

proanthocyanidinSARS-CoV-2tannic acidteaUHPLC-HRMS

Identifiers

PMID38859869
PMCPMC11162682

What Socratic holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.