Evidence mapPaperPMID 38860973Full record

Trial reportGut microbes

Adaptation to tolerate high doses of arabinoxylan is associated with fecal levels of

Edward C Deehan, Zhengxiao Zhang, Nguyen K Nguyen, Maria Elisa Perez-Muñoz, Janis Cole, Alessandra Riva, David Berry, Carla M Prado, Jens Walter

Abstract readRandomized Controlled Trial
In one paragraph

Trial report in Gut microbes. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed.

  1. Article
  2. Development of a Novel Probiotic Strain with Digestion Functionality,Journal of microbiology and biotechnology · 2025
    Article
  3. Article
  4. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors.

Edward C DeehanDepartment of Agricultural, Food and Nutritional Science, University of Alberta, Edmonton, Canada.ORCID 0000-0001-7697-1418
Zhengxiao ZhangDepartment of Medicine, University of Alberta, Edmonton, Canada.ORCID 0000-0002-6977-4309
Nguyen K NguyenDepartment of Agricultural, Food and Nutritional Science, University of Alberta, Edmonton, Canada.
Maria Elisa Perez-MuñozDepartment of Agricultural, Food and Nutritional Science, University of Alberta, Edmonton, Canada.
Janis ColeDepartment of Agricultural, Food and Nutritional Science, University of Alberta, Edmonton, Canada.
Alessandra RivaCentre for Microbiology and Environmental Systems Science, Department of Microbiology and Ecosystem Science, Division of Microbial Ecology, University of Vienna, Vienna, Austria.
David BerryCentre for Microbiology and Environmental Systems Science, Department of Microbiology and Ecosystem Science, Division of Microbial Ecology, University of Vienna, Vienna, Austria.
Carla M PradoDepartment of Agricultural, Food and Nutritional Science, University of Alberta, Edmonton, Canada.
Jens WalterDepartment of Agricultural, Food and Nutritional Science, University of Alberta, Edmonton, Canada.ORCID 0000-0003-1754-172X

Funding

European Research Council 741623
6 · The paper itself

Abstract

Dietary fiber supplements are a strategy to close the 'fiber gap' and induce targeted modulations of the gut microbiota. However, higher doses of fiber supplements cause gastrointestinal (GI) symptoms that differ among individuals. What determines these inter-individual differences is insufficiently understood. Here we analyzed findings from a six-week randomized controlled trial that evaluated GI symptoms to corn bran arabinoxylan (AX;

Indexed as

Bifidobacterium longumDietary FiberFecesGastrointestinal MicrobiomeXylansAdaptation, PhysiologicalAdultAgedDietary SupplementsFemaleFermentationHumansMaleMiddle AgedarabinoxylanDietary FiberXylansAdultsarabinoxylanBifidobacteriumdietary fibergastrointestinal symptomsgut microbiomeshort-chain fatty acidstolerance

Identifiers

PMID38860973
PMCPMC11174067

What Socratic holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.