Evidence map›Paper›PMID 38862021›Full record

ArticleOpen biology2024

Kinetoplastid kinetochore proteins KKT14-KKT15 are divergent Bub1/BubR1-Bub3 proteins.

Daniel Ballmer, William Carter, Jolien J E van Hooff, Eelco C Tromer, Midori Ishii, Patryk Ludzia, Bungo Akiyoshi

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Open biology, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

6 citing papers in PubMed.

  1. Article
  2. Revisiting the question: When is a centromere not a kinetochore?Chromosome research : an international journal on the molecular, supramolecular and evolutionary aspects of chromosome biology · 2025
    Review
  3. Article
  4. Article
  5. Article
  6. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Daniel Ballmer *Department of Biochemistry, University of Oxford , Oxford OX1 3QU, UK.ORCID 0000-0002-1966-0960
William Carter *Department of Biochemistry, University of Oxford , Oxford OX1 3QU, UK.
Jolien J E van HooffLaboratory of Microbiology, Department of Agrotechnology and Food Sciences, Wageningen University and Research , 6708 HB Wageningen, The Netherlands.ORCID 0000-0001-8754-1894
Eelco C TromerCell Biochemistry, Groningen Biomolecular Sciences and Biotechnology Institute, Faculty of Science and Engineering, University of Groningen , 9747 AG Groningen, The Netherlands.ORCID 0000-0003-3540-7727
Midori IshiiDepartment of Biochemistry, University of Oxford , Oxford OX1 3QU, UK.
Patryk LudziaDepartment of Biochemistry, University of Oxford , Oxford OX1 3QU, UK.
Bungo AkiyoshiDepartment of Biochemistry, University of Oxford , Oxford OX1 3QU, UK.ORCID 0000-0001-6010-394X

Funding

Nederlandse Organisatie voor Wetenschappelijk OnderzoekWellcome / EPSRC Centre for Interventional and Surgical SciencesWellcome Trust
6 · The paper itself

Abstract

Faithful transmission of genetic material is crucial for the survival of all organisms. In many eukaryotes, a feedback control mechanism called the spindle checkpoint ensures chromosome segregation fidelity by delaying cell cycle progression until all chromosomes achieve proper attachment to the mitotic spindle. Kinetochores are the macromolecular complexes that act as the interface between chromosomes and spindle microtubules. While most eukaryotes have canonical kinetochore proteins that are widely conserved, kinetoplastids such as

Indexed as

KinetochoresProtozoan ProteinsAmino Acid SequenceCell Cycle ProteinsChromosome SegregationCrystallography, X-RayModels, MolecularPhylogenyProtein BindingProtein Serine-Threonine KinasesTrypanosoma brucei bruceiCell Cycle ProteinsProtein Serine-Threonine KinasesProtozoan Proteinschromosome segregationkinetochorekinetoplastidspindle checkpointTrypanosoma brucei

Identifiers

PMID38862021
PMCPMC11286163

What Socratic holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.