Evidence map›Paper›PMID 38865175›Full record

ArticleeLife2024

RAPSYN-mediated neddylation of BCR-ABL alternatively determines the fate of Philadelphia chromosome-positive leukemia.

Mengya Zhao, Beiying Dai, Xiaodong Li, Yixin Zhang, Chun Qiao, Yaru Qin, Zhao Li, Qingmei Li, Shuzhen Wang, Yong Yang and 1 more

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in eLife, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed.

  1. Review
  2. Neddylation E1 Obligatory Subunit Nae1 Is Critical to Neuromuscular Junction Development and Maintenance.The Journal of neuroscience : the official journal of the Society for Neuroscience · 2025
    Article
  3. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors.

Mengya Zhao *Laboratory of Chemical Biology, School of Life Science and Technology, China Pharmaceutical University, Nanjing, China.ORCID https://orcid.org/0000-0002-6339-1892
Beiying Dai *State Key Laboratory of Natural Medicines, China Pharmaceutical University, Nanjing, China.
Xiaodong Li *Laboratory of Chemical Biology, School of Life Science and Technology, China Pharmaceutical University, Nanjing, China.
Yixin Zhang *State Key Laboratory of Natural Medicines, China Pharmaceutical University, Nanjing, China.
Chun QiaoState Key Laboratory of Natural Medicines, China Pharmaceutical University, Nanjing, China.
Yaru QinState Key Laboratory of Natural Medicines, China Pharmaceutical University, Nanjing, China.
Zhao LiLaboratory of Chemical Biology, School of Life Science and Technology, China Pharmaceutical University, Nanjing, China.
Qingmei LiLaboratory of Chemical Biology, School of Life Science and Technology, China Pharmaceutical University, Nanjing, China.
Shuzhen WangLaboratory of Chemical Biology, School of Life Science and Technology, China Pharmaceutical University, Nanjing, China.ORCID https://orcid.org/0000-0003-3869-2463
Yong YangState Key Laboratory of Natural Medicines, China Pharmaceutical University, Nanjing, China.
Yijun ChenLaboratory of Chemical Biology, School of Life Science and Technology, China Pharmaceutical University, Nanjing, China.ORCID https://orcid.org/0000-0002-4920-152X

Funding

"Double First-Class" University Project CPU2022QZ014Key Research and Development Project of Guangdong Province 2022B1111070004National Key Research and Development Program of China 2018YFA0902000National Natural Science Foundation of China 81872924National Natural Science Foundation of China 81973386National Natural Science Foundation of China 82002971Project Program of the State Key Laboratory of Natural Medicines SKLNMZZ202201
6 · The paper itself

Abstract

Philadelphia chromosome-positive (Ph

Indexed as

Fusion Proteins, bcr-ablLeukemia, Myelogenous, Chronic, BCR-ABL PositiveMuscle ProteinsAnimalsCell Line, TumorHumansMiceNEDD8 ProteinUbiquitin-Protein LigasesFusion Proteins, bcr-ablMuscle ProteinsNEDD8 ProteinNEDD8 protein, humanperipheral membrane protein 43KUbiquitin-Protein Ligasescancer biologycell biologyE. colihumanmouse

Identifiers

PMID38865175
PMCPMC11168747

What Socratic holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.