Evidence mapPaperPMID 38866976Full record

Trial reportEuropean journal of clinical nutrition2024

Effect of time restricted eating versus daily calorie restriction on sex hormones in males and females with obesity.

Shuhao Lin, Sofia Cienfuegos, Mark Ezpeleta, Vasiliki Pavlou, Mary-Claire Runchey, Krista A Varady

Abstract readRandomized Controlled Trial
PubMed Publisher
In one paragraph

Trial report in European journal of clinical nutrition, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed
field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

6 citing papers in PubMed.

  1. Trial
  2. Review
  3. Review
  4. Review
  5. Review
  6. Review
4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

6 authors.

Shuhao LinDepartment of Kinesiology and Nutrition, University of Illinois at Chicago, Chicago, IL, USA.
Sofia CienfuegosDepartment of Kinesiology and Nutrition, University of Illinois at Chicago, Chicago, IL, USA.
Mark EzpeletaDepartment of Kinesiology and Nutrition, University of Illinois at Chicago, Chicago, IL, USA.ORCID http://orcid.org/0000-0002-0746-2414
Vasiliki PavlouDepartment of Kinesiology and Nutrition, University of Illinois at Chicago, Chicago, IL, USA.ORCID http://orcid.org/0000-0001-9486-9310
Mary-Claire RuncheyDepartment of Kinesiology and Nutrition, University of Illinois at Chicago, Chicago, IL, USA.
Krista A VaradyDepartment of Kinesiology and Nutrition, University of Illinois at Chicago, Chicago, IL, USA. varady@uic.edu.ORCID http://orcid.org/0000-0002-9279-9934

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

This study examined the effects of time restricted eating (TRE) on sex hormones in males and females, versus daily calorie restriction (CR). Adults with obesity (n = 90) were randomized to 1 of 3 groups for 12-months: 8-h TRE (eating only between 12:00 to 8:00 pm, with no calorie counting); CR (25% energy restriction daily); or control. Body weight decreased (P < 0.01) in the TRE and CR groups, relative to controls, in males, premenopausal females, and postmenopausal females, by month 12. Total testosterone, dehydroepiandrosterone (DHEA), and sex hormone binding globulin (SHBG) levels did not change over time, or between groups, in males, premenopausal females, and postmenopausal females. Estradiol, estrone, and progesterone were only measured in postmenopausal females, and remained unchanged. These findings suggest that TRE produces significant weight loss but does not impact circulating sex hormone levels in males and females with obesity over 12 months, relative to CR and controls.

Indexed as

Caloric RestrictionGonadal Steroid HormonesObesitySex Hormone-Binding GlobulinTestosteroneWeight LossAdultAgedDehydroepiandrosteroneDiet, ReducingEstradiolFemaleHumansIntermittent FastingMaleMiddle AgedDehydroepiandrosteroneEstradiolGonadal Steroid HormonesProgesteroneSex Hormone-Binding GlobulinTestosterone

Identifiers

PMID38866976

What Socratic holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.