Evidence mapPaperPMID 38868849Full record

ArticleNoro psikiyatri arsivi2024

The Role of Sertoli Cell Hormones in Male Preponderance Observed in Autism Spectrum Disorder.

Şeyda Çelik Göksoy, Yaşar Tanır, Nusret Soylu, Adile Merve Baki, Pervin Vural, Ali Karayağmurlu

Abstract read
In one paragraph

Article in Noro psikiyatri arsivi, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Şeyda Çelik GöksoyIstanbul University, Istanbul Medical Faculty, Department of Child and Adolescent Psychiatry Istanbul, Turkey.
Yaşar TanırIstanbul University, Istanbul Medical Faculty, Department of Child and Adolescent Psychiatry Istanbul, Turkey.
Nusret SoyluIstanbul University, Istanbul Medical Faculty, Department of Child and Adolescent Psychiatry Istanbul, Turkey.
Adile Merve BakiIstanbul University, Istanbul Medical Faculty, Department of Biochemistry, Istanbul, Turkey.
Pervin VuralIstanbul University, Istanbul Medical Faculty, Department of Biochemistry, Istanbul, Turkey.
Ali KarayağmurluIstanbul University, Istanbul Medical Faculty, Department of Child and Adolescent Psychiatry Istanbul, Turkey.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Introduction: There is a significant, but poorly understood, male preponderance in prevalence of autism spectrum disorder (ASD). The aim of this study was to examine the relationship between male preponderance in ASD and Inhibin B (InhB) and Anti-Müllerian hormone (AMH) levels and the 2D/4D finger ratio associated with fetal androgen exposure. Methods: 42 patients with ASD and 42 neurotypical controls between the ages of 5 and 10 were included. ASD diagnosis and severity were determined using K-SADS PL (Kiddie-SADS - Present and Life Time) Version 2016 and the Childhood Autism Rating Scale (CARS). Serum InhB and AMH were measured. The 2D/4D finger length ratio was also calculated for hand anthropometric measurements. Results: Serum InhB levels were higher in children diagnosed with ASD compared to the neurotypical controls (p=0.003). Serum AMH levels were similar in both groups. Positive correlation was determined between AMH and CARS scores (r=0.315, p=0.05). 2D/4D finger ratios in the ASD group were significantly lower than in the control group (p<0.001). Conclusion: The study findings suggest that InhB, AMH, and fetal testosterone may be associated with male preponderance in ASD. More research is now required for a better understanding of this subject.

Indexed as

Anti-müllerian hormoneautism spectrum disorderinhibin Bmale preponderance

Identifiers

PMID38868849
PMCPMC11165613

What Socratic holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.