Evidence map›Paper›PMID 38870902›Full record

ReviewCell host & microbe2024

Nutrient acquisition strategies by gut microbes.

Matthew K Muramatsu, Sebastian E Winter

Abstract readReview
In one paragraph

Review in Cell host & microbe, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 31 papers.

0numbers the graph read from it
0cells of the map it votes in
31citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

31 citing papers in PubMed.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

2 authors.

Matthew K MuramatsuDepartment of Internal Medicine, Division of Infectious Diseases, UC Davis, Davis, CA 95616, USA.
Sebastian E WinterDepartment of Internal Medicine, Division of Infectious Diseases, UC Davis, Davis, CA 95616, USA. Electronic address: sebwinter@ucdavis.edu.

Funding

Central metabolism of Salmonella in the inflamed gutR01AI118807 · NIAID · UT SOUTHWESTERN MEDICAL CENTER · PI Sebastian E Winter · 2015 to 2026
$5.3M
Glutarate metabolism in SalmonellaR21AI166263 · NIAID · UT SOUTHWESTERN MEDICAL CENTER · PI WINTER, SEBASTIAN E · 2021 to 2022
$444k
Metabolic Interactions between Salmonella and E. coli Nissle 1917R21AI171537 · NIAID · UNIVERSITY OF CALIFORNIA AT DAVIS · PI WINTER, SEBASTIAN E · 2022 to 2023
$439k
NIAID NIH HHS L30 AI066263NIAID NIH HHS R01 AI118807NIAID NIH HHS R21 AI166263NIAID NIH HHS R21 AI171537
6 · The paper itself

Abstract

The composition and function of the gut microbiota are intimately tied to nutrient acquisition strategies and metabolism, with significant implications for host health. Both dietary and host-intrinsic factors influence community structure and the basic modes of bacterial energy metabolism. The intestinal tract is rich in carbon and nitrogen sources; however, limited access to oxygen restricts energy-generating reactions to fermentation. By contrast, increased availability of electron acceptors during episodes of intestinal inflammation results in phylum-level changes in gut microbiota composition, suggesting that bacterial energy metabolism is a key driver of gut microbiota function. In this review article, we will illustrate diverse examples of microbial nutrient acquisition strategies in the context of habitat filters and anatomical location and the central role of energy metabolism in shaping metabolic strategies to support bacterial growth in the mammalian gut.

Indexed as

BacteriaEnergy MetabolismGastrointestinal MicrobiomeNutrientsAnimalsCarbonFermentationGastrointestinal TractHumansNitrogenCarbonNitrogenNutrientsbacterial metabolismfermentationgut microbiotarespiration

Identifiers

PMID38870902
PMCPMC11178278

What Socratic holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.