Evidence mapPaperPMID 38879626Full record

ArticlePediatric research2025

Evaluation of epicardial adipose tissue in children with type 1 diabetes.

Gül Trabzon, Şükrü Güngör, Şeyma Demiray Güllü, Osman Fırat Çalışkan, Ufuk Utku Güllü

Abstract read
In one paragraph

Article in Pediatric research, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed
field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

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Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

6 citing papers in PubMed.

  1. Review
  2. Article
  3. Review
  4. Epicardial adipose tissue in type 1 diabetes mellitus: a systematic review and meta-analysis.The Egyptian heart journal : (EHJ) : official bulletin of the Egyptian Society of Cardiology · 2025
    Review
  5. Review
  6. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Gül TrabzonHatay Mustafa Kemal University Medical Faculty Department of Pediatric Endocrinology, Hatay, Turkey. gldirekk@gmail.com.ORCID http://orcid.org/0000-0002-9262-5678
Şükrü GüngörInonu University Medical Faculty Department of Pediatric Gastroenterology, Malatya, Turkey.ORCID http://orcid.org/0000-0002-0433-5970
Şeyma Demiray GüllüHatay Mustafa Kemal University Medical Faculty Department of Pediatrics, Hatay, Turkey.ORCID http://orcid.org/0000-0003-3596-2704
Osman Fırat ÇalışkanHatay Mustafa Kemal University Medical Faculty Department of Pediatrics, Hatay, Turkey.ORCID http://orcid.org/0009-0007-4991-1955
Ufuk Utku GüllüHatay Mustafa Kemal University Medical Faculty Department of Pediatric Cardiology, Hatay, Turkey.ORCID http://orcid.org/0000-0002-5561-3598

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

introductionEpicardial adipose tissue (EAT), the visceral fat surrounding the heart between the myocardium and visceral pericardium, intersects with Type 1 diabetes (T1D). This review aims to elucidate the intricate association between EAT and childhood T1D. MATERIALS AND

methodsIn this retrospective study, two pediatric groups were involved children with type 1 diabetes, and healthy children. Epicardial fat thickness was measured appropriately, and the study documented HbA1c levels and time to diabetes diagnosis for comprehensive analysis.

resultsEncompassing 51 children with T1D and 69 healthy controls, revealed that children with type 1 diabetes had a mean HbA1c level of 9.4 ± 0.2, and a mean insulin dose of 0.94 units/kg/day. Epicardial adipose tissue (EAT) values were significantly higher in the Type 1 DM group. It has been shown that epicardial fat thickness may have a specific and sensitive value in type 1 diabetics. DISCUSSION: The increased presence of epicardial fat tissue in children with type 1 diabetes is highlighted, prompting the consideration of various mechanisms. However, the complexity of this relationship underscores the need for further studies to provide a more comprehensive understanding of the underlying factors. Ongoing research in this area is crucial for advancing our knowledge and potential therapeutic interventions. IMPACTS: Cardiac complications are one of the most important causes of morbidity and mortality in people with type 1 diabetes. Being able to detect cardiological complications of diabetes at an early stage contributes to morbidity. We found that epicardial fat tissue thickness was thicker in children with type 1 diabetes than in healthy children. Epicardial fat tissue thickness may be associated with poor control in children with type 1 diabetes and maybe a guide in terms of cardiac risks.

Indexed as

Adipose TissueDiabetes Mellitus, Type 1PericardiumAdolescentCase-Control StudiesChildChild, PreschoolEpicardial Adipose TissueFemaleGlycated HemoglobinHumansMaleRetrospective StudiesGlycated Hemoglobinhemoglobin A1c protein, human

Identifiers

PMID38879626
PMCPMC11798853

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.