Evidence map›Paper›PMID 38879846›Full record

ReviewNeuroscience bulletin2025

Crosstalk Between the Nervous System and Colorectal Cancer.

Xi Li, Chunshui Ye, Min Wang, Patrick Kwan, Xin Tian, Yanke Zhang

Abstract readReview
In one paragraph

Review in Neuroscience bulletin, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers.

0numbers the graph read from it
0cells of the map it votes in
7citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

7 citing papers in PubMed.

  1. Review
  2. Review
  3. Article
  4. Article
  5. Review
  6. Article
  7. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Xi Li *Jining Medical University, Jining, 272000, China.
Chunshui Ye *Department of Gastrointestinal Surgery, Jining No. 1 People's Hospital, Jining, 272000, China.
Min WangDepartment of Neurology, Renji Hospital, Shanghai Jiaotong University School of Medicine, Shanghai, 200127, China.
Patrick KwanDepartment of Neurology, The First Affiliated Hospital of Chongqing Medical University, Chongqing Key Laboratory of Neurology, Chongqing, 400016, China. patrick.kwan@monash.edu.ORCID http://orcid.org/0000-0001-7310-276X
Xin TianDepartment of Neurology, The First Affiliated Hospital of Chongqing Medical University, Chongqing Key Laboratory of Neurology, Chongqing, 400016, China. xintian@cqmu.edu.cn.ORCID http://orcid.org/0000-0003-1552-8919
Yanke ZhangDepartment of Neurology, Affiliated Hospital of Jining Medical University, Jining, 272000, China. yankezhang@mail.jnmc.edu.cn.ORCID http://orcid.org/0000-0003-4788-8708

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The nervous system is the dominant regulatory system in the human body. The traditional theory is that tumors lack innervation. However, an increasing number of studies have shown complex bidirectional interactions between tumors and the nervous system. Globally, colorectal cancer (CRC) is the third most common cancer. With the rise of tumor neuroscience, the role of nervous system imbalances in the occurrence and development of CRC has attracted increasing amounts of attention. However, there are still many gaps in the research on the interactions and mechanisms involved in the nervous system in CRC. This article systematically reviews emerging research on the bidirectional relationships between the nervous system and CRC, focusing on the following areas: (1) Effects of the nervous system on colon cancer. (2) Effects of CRC on the nervous system. (3) Treatment of CRC associated with the nervous system.

Indexed as

Colorectal NeoplasmsNervous SystemAnimalsHumansCancer treatmentColorectal cancerNervous systemTumor microenvironmentTumor neuroscience

Identifiers

PMID38879846
PMCPMC11748644

What Socratic holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.