Evidence map›Paper›PMID 38882678›Full record

ArticleComputational and structural biotechnology journal2024

Dynamic expedition of leading mutations in SARS-CoV-2 spike glycoproteins.

Muhammad Hasan, Zhouyi He, Mengqi Jia, Alvin C F Leung, Kathiresan Natarajan, Wentao Xu, Shanqi Yap, Feng Zhou, Shihong Chen, Hailei Su and 2 more

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Computational and structural biotechnology journal, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Article
  2. Decoding the cross-immune pressure: Dengue's role in SARS-CoV-2 evolution.Computational and structural biotechnology journal · 2025
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

12 authors.

Muhammad HasanDepartment of Chemistry, The Hong Kong University of Science and Technology, Clear Water Bay, Hong Kong, China.
Zhouyi HeDepartment of Chemistry, The Hong Kong University of Science and Technology, Clear Water Bay, Hong Kong, China.
Mengqi JiaDepartment of Chemistry, The Hong Kong University of Science and Technology, Clear Water Bay, Hong Kong, China.
Alvin C F LeungDepartment of Chemistry, The Hong Kong University of Science and Technology, Clear Water Bay, Hong Kong, China.
Kathiresan NatarajanRajiv Gandhi Centre for Biotechnology, Thiruvananthapuram 695014, Kerala, India.
Wentao XuDepartment of Chemistry, The Hong Kong University of Science and Technology, Clear Water Bay, Hong Kong, China.
Shanqi YapDepartment of Chemistry, The Hong Kong University of Science and Technology, Clear Water Bay, Hong Kong, China.
Feng ZhouDepartment of Chemistry, The Hong Kong University of Science and Technology, Clear Water Bay, Hong Kong, China.
Shihong ChenDepartment of Chemistry, The Hong Kong University of Science and Technology, Clear Water Bay, Hong Kong, China.
Hailei SuBengbu Hospital of Traditional Chinese Medicine, 4339 Huai-shang Road, Anhui 233080, China.
Kaicheng ZhuDepartment of Chemistry, The Hong Kong University of Science and Technology, Clear Water Bay, Hong Kong, China.
Haibin SuDepartment of Chemistry, The Hong Kong University of Science and Technology, Clear Water Bay, Hong Kong, China.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The continuous evolution of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), which caused the recent pandemic, has generated countless new variants with varying fitness. Mutations of the spike glycoprotein play a particularly vital role in shaping its evolutionary trajectory, as they have the capability to alter its infectivity and antigenicity. We present a time-resolved statistical method, Dynamic Expedition of Leading Mutations (deLemus), to analyze the evolutionary dynamics of the SARS-CoV-2 spike glycoprotein. The proposed

Identifiers

PMID38882678
PMCPMC11176665

What Socratic holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.