Evidence map›Paper›PMID 38884785›Full record

ArticleBiological cybernetics2024

COVID-19 and silent hypoxemia in a minimal closed-loop model of the respiratory rhythm generator.

Casey O Diekman, Peter J Thomas, Christopher G Wilson

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Biological cybernetics, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

3 authors.

Casey O DiekmanDepartment of Mathematical Sciences, New Jersey Institute of Technology, University Heights, Newark, NJ, 07102, USA. diekman@njit.edu.
Peter J ThomasDepartment of Mathematics, Applied Mathematics and Statistics, Case Western Reserve University, 10900 Euclid Avenue, Cleveland, OH, 44106, USA.
Christopher G WilsonDepartment of Pediatrics and Basic Sciences, Lawrence D. Longo, MD Center for Perinatal Biology, Loma Linda University, 11223 Campus St, Loma Linda, CA, 92350, USA.

Funding

A novel approach to analyzing functional connectomics and combinatorial control in a tractable small-brain closed-loop systemRF1NS118606 · NINDS · UNIVERSITY OF TEXAS HLTH SCI CTR HOUSTON · PI BYRNE, JOHN H, CHESTEK, CYNTHIA ANNE · 2020 to 2020
$3.0M
Unravelling lung interoception and its functional consequence in the developing ovine lungR01AT011691 · NCCIH · LOMA LINDA UNIVERSITY · PI BLOOD, ARLIN B, WILSON, CHRISTOPHER G · 2021 to 2025
$2.7M
National Science Foundation DMS-1555237NCCIH NIH HHS R01 AT011691NIH HHS RF1 NS118606-01NINDS NIH HHS RF1 NS118606
6 · The paper itself

Abstract

Silent hypoxemia, or "happy hypoxia," is a puzzling phenomenon in which patients who have contracted COVID-19 exhibit very low oxygen saturation (

Indexed as

COVID-19HypoxiaHumansOxygenRespirationSARS-CoV-2OxygenBreathing controlCentral pattern generatorComputational modelingCOVID-19PolycythemiaSensory feedbackSilent hypoxemia

Identifiers

PMID38884785
PMCPMC11289179

What Socratic holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.