Evidence mapPaperPMID 38890721Full record

ReviewJournal of nanobiotechnology2024

Advances in nanomaterial-targeted treatment of acute lung injury after burns.

Shuo Zhang, Xinyu Zhao, Yuhao Xue, Xianwen Wang, Xu-Lin Chen

Abstract readReview
In one paragraph

Review in Journal of nanobiotechnology, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 16 papers.

0numbers the graph read from it
0cells of the map it votes in
16citing papers in PubMed
field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

16 citing papers in PubMed.

  1. Review
  2. Article
  3. Article
  4. Review
  5. Article
  6. Review
  7. Review
  8. Review
  9. Review
  10. [Advances in inhalable nano-formulations].Zhejiang da xue xue bao. Yi xue ban = Journal of Zhejiang University. Medical sciences · 2025
    Review
  11. Article
  12. [Amentoflavone alleviates acute lung injury in mice by inhibiting cell pyroptosis].Nan fang yi ke da xue xue bao = Journal of Southern Medical University · 2025
    Article
  13. Article
  14. Article
  15. Review
  16. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Shuo Zhang *Department of Burns, The First Affiliated Hospital of Anhui Medical University, Hefei, 230022, P. R. China.
Xinyu Zhao *Department of Burns, The First Affiliated Hospital of Anhui Medical University, Hefei, 230022, P. R. China.
Yuhao Xue *School of Biomedical Engineering, Anhui Medical University, Hefei, 230022, P. R. China.
Xianwen WangSchool of Biomedical Engineering, Anhui Medical University, Hefei, 230022, P. R. China. xianwenwang@ahmu.edu.cn.
Xu-Lin ChenDepartment of Burns, The First Affiliated Hospital of Anhui Medical University, Hefei, 230022, P. R. China. okcxl@126.com.

Funding

National Natural Science Foundation of China 52202343, 82172204the Anhui Key Research and Development Plan 202104j07020027the Basic and Clinical Cooperative Research and Promotion Program of Anhui Medical University 2021xkT028the Research Fund of Anhui Institute of Translational Medicine 2022zhyx-C01
6 · The paper itself

Abstract

Acute lung injury (ALI) is a common complication in patients with severe burns and has a complex pathogenesis and high morbidity and mortality rates. A variety of drugs have been identified in the clinic for the treatment of ALI, but they have toxic side effects caused by easy degradation in the body and distribution throughout the body. In recent years, as the understanding of the mechanism underlying ALI has improved, scholars have developed a variety of new nanomaterials that can be safely and effectively targeted for the treatment of ALI. Most of these methods involve nanomaterials such as lipids, organic polymers, peptides, extracellular vesicles or cell membranes, inorganic nanoparticles and other nanomaterials, which are targeted to reach lung tissues to perform their functions through active targeting or passive targeting, a process that involves a variety of cells or organelles. In this review, first, the mechanisms and pathophysiological features of ALI occurrence after burn injury are reviewed, potential therapeutic targets for ALI are summarized, existing nanomaterials for the targeted treatment of ALI are classified, and possible problems and challenges of nanomaterials in the targeted treatment of ALI are discussed to provide a reference for the development of nanomaterials for the targeted treatment of ALI.

Indexed as

Acute Lung InjuryBurnsNanostructuresAnimalsDrug Delivery SystemsHumansLungNanoparticlesALIBurnCamouflaged nanoparticlesNanomaterialsTargeted treatment

Identifiers

PMID38890721
PMCPMC11184898

What Socratic holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.