Evidence map›Paper›PMID 38892031›Full record

ArticleInternational journal of molecular sciences2024

Unveiling the Influence of Copy Number Variations on Genetic Diversity and Adaptive Evolution in China's Native Pig Breeds via Whole-Genome Resequencing.

Haonan Yuan, Wenjing Wei, Yue Zhang, Changwen Li, Shengguo Zhao, Zhe Chao, Changyou Xia, Jinqiang Quan, Caixia Gao

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in International journal of molecular sciences, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers.

0numbers the graph read from it
0cells of the map it votes in
8citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

8 citing papers in PubMed.

  1. Article
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  5. Article
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  7. Article
  8. Gene Editing for Enhanced Swine Production: Current Advances and Prospects.Animals : an open access journal from MDPI · 2025
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors.

Haonan YuanCollege of Animal Science and Technology, Gansu Agricultural University, Lanzhou 730030, China.
Wenjing WeiCollege of Animal Science and Technology, Gansu Agricultural University, Lanzhou 730030, China.
Yue ZhangCollege of Animal Science and Technology, Gansu Agricultural University, Lanzhou 730030, China.
Changwen LiState Key Laboratory for Animal Disease Control and Prevention, Harbin Veterinary Research Institute, Chinese Academy of Agricultural Sciences (CAAS), Heilongjiang Provincial Key Laboratory of Laboratory Animal and Comparative Medicine, National Poultry Laboratory Animal Resource Center, Harbin 150069, China.
Shengguo ZhaoCollege of Animal Science and Technology, Gansu Agricultural University, Lanzhou 730030, China.ORCID 0000-0001-8744-375X
Zhe ChaoInstitute of Animal Science and Veterinary Medicine, Hainan Academy of Agricultural Sciences, Key Laboratory of Tropical Animal Breeding and Disease Research, Haikou 571100, China.
Changyou XiaState Key Laboratory for Animal Disease Control and Prevention, Harbin Veterinary Research Institute, Chinese Academy of Agricultural Sciences (CAAS), Heilongjiang Provincial Key Laboratory of Laboratory Animal and Comparative Medicine, National Poultry Laboratory Animal Resource Center, Harbin 150069, China.
Jinqiang QuanCollege of Animal Science and Technology, Gansu Agricultural University, Lanzhou 730030, China.
Caixia GaoState Key Laboratory for Animal Disease Control and Prevention, Harbin Veterinary Research Institute, Chinese Academy of Agricultural Sciences (CAAS), Heilongjiang Provincial Key Laboratory of Laboratory Animal and Comparative Medicine, National Poultry Laboratory Animal Resource Center, Harbin 150069, China.

Funding

Central Public-interest Scientific Institution Basal Research Fund 1610302020008, 1610302022018National Center of Technology Innovation for Pigs NCTIP-XD1C09the National Key R&D Program of China 2021YFF0703000
6 · The paper itself

Abstract

Copy number variations (CNVs) critically influence individual genetic diversity and phenotypic traits. In this study, we employed whole-genome resequencing technology to conduct an in-depth analysis of 50 pigs from five local swine populations [Rongchang pig (RC), Wuzhishan pig (WZS), Tibetan pig (T), Yorkshire (YL) and Landrace (LR)], aiming to assess their genetic potential and explore their prospects in the field of animal model applications. We identified a total of 96,466 CNVs, which were subsequently integrated into 7112 non-redundant CNVRs, encompassing 1.3% of the swine genome. Functional enrichment analysis of the genes within these CNVRs revealed significant associations with sensory perception, energy metabolism, and neural-related pathways. Further selective scan analyses of the local pig breeds RC, T, WZS, along with YL and LR, uncovered that for the RC variety, the genes

Indexed as

DNA Copy Number VariationsWhole Genome SequencingAnimalsBreedingChinaEvolution, MolecularGenetic VariationGenomeSwineanimal model applicationsgene–environment interactiongenomic analysisselective breedingswine genomics

Identifiers

PMID38892031
PMCPMC11172908

What Socratic holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.