Evidence mapPaperPMID 38892505Full record

Trial reportNutrients2024

Prebiotic Treatment in Patients with Nonalcoholic Fatty Liver Disease (NAFLD)-A Randomized Pilot Trial.

Naama Reshef, Uri Gophna, Leah Reshef, Fred Konikoff, Gila Gabay, Taiba Zornitzki, Hilla Knobler, Yaakov Maor

Abstract readRandomized Controlled Trial
In one paragraph

Trial report in Nutrients, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 16 papers, 3 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
16citing papers in PubMed, 3 pooled it
field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

16 citing papers in PubMed, 3 syntheses or guidelines pooled it.

  1. Pooled it
  2. Pooled it
  3. Pooled it
  4. Trial
  5. Review
  6. Review
  7. Review
  8. Article
  9. Dietary fibre and the gut microbiome: implications for glucose homeostasis.Current opinion in clinical nutrition and metabolic care · 2025
    Review
  10. Review
  11. Review
  12. Review
  13. Review
  14. Review
  15. Review
  16. Gut microbiome in non-alcoholic fatty liver disease.Frontiers in gastroenterology (Lausanne, Switzerland) · 2024
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Naama ReshefInstitute of Diabetes and Metabolism-Kaplan Medical Center, Rehovot 7661041, Israel.
Uri GophnaShmunis School of Biomedicine and Cancer Research, Faculty of Life Sciences, Tel-Aviv University, Tel Aviv 6423906, Israel.ORCID 0000-0001-5129-5652
Leah ReshefShmunis School of Biomedicine and Cancer Research, Faculty of Life Sciences, Tel-Aviv University, Tel Aviv 6423906, Israel.
Fred KonikoffInstitute of Gastroenterology and Hepatology-Meir Medical Center, Kefar Sava 4428164, Israel.
Gila GabayInstitute of Gastroenterology and Hepatology-Meir Medical Center, Kefar Sava 4428164, Israel.
Taiba ZornitzkiInstitute of Diabetes and Metabolism-Kaplan Medical Center, Rehovot 7661041, Israel.
Hilla KnoblerInstitute of Diabetes and Metabolism-Kaplan Medical Center, Rehovot 7661041, Israel.
Yaakov MaorHadassah School of Medicine, The Hebrew University, Jerusalem 9112102, Israel.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Several studies show that gut microbiotas in patients with nonalcoholic fatty liver disease (NAFLD) differ from those in a healthy population, suggesting that this alteration plays a role in NAFLD pathogenesis. We investigated whether prebiotic administration affects liver fat content and/or liver-related and metabolic parameters. Patients with NAFLD and metabolic syndrome (age: 50 ± 11; 79% men) were randomized to receive either 16 g/day of prebiotic (ITFs-inulin-type fructans) (

Indexed as

FecesGastrointestinal MicrobiomeLiverNon-alcoholic Fatty Liver DiseasePrebioticsAdultBifidobacteriumDouble-Blind MethodFemaleHumansMaleMetabolic SyndromeMiddle AgedPilot ProjectsPrebioticsfibroblast growth factorlipopolysaccharidemicrobiotaNAFLDprebiotic

Identifiers

PMID38892505
PMCPMC11174003

What Socratic holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.