Evidence map›Paper›PMID 38892541›Full record

ArticleNutrients2024

Metabolic and Low-Grade Inflammation Risk in Young Adults with a History of Extrauterine Growth Restriction.

Laura Palomino-Fernández, Belén Pastor-Villaescusa, Inmaculada Velasco, María de la Cruz Rico, Juan Roa, Ángel Gil, Mercedes Gil-Campos

Abstract read
In one paragraph

Article in Nutrients, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Article
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Laura Palomino-FernándezMetabolism and Investigation Unit, Reina Sofia University Hospital, Maimonides Institute of Biomedicine Research of Cordoba (IMIBIC), University of Cordoba, 14004 Cordoba, Spain.ORCID 0009-0008-5942-7240
Belén Pastor-VillaescusaMetabolism and Investigation Unit, Reina Sofia University Hospital, Maimonides Institute of Biomedicine Research of Cordoba (IMIBIC), University of Cordoba, 14004 Cordoba, Spain.ORCID 0000-0003-0817-6804
Inmaculada VelascoDepartment of Cell Biology, Physiology and Immunology, Reina Sofia University Hospital, Maimonides Institute of Biomedicine Research of Cordoba (IMIBIC), University of Cordoba, 14004 Cordoba, Spain.
María de la Cruz RicoDepartment of Biochemistry and Molecular Biology II, School of Pharmacy, "José Mataix Verdú" Institute of Nutrition and Food Technology (INYTA), University of Granada, 18016 Granada, Spain.
Juan RoaDepartment of Cell Biology, Physiology and Immunology, Reina Sofia University Hospital, Maimonides Institute of Biomedicine Research of Cordoba (IMIBIC), University of Cordoba, 14004 Cordoba, Spain.
Ángel GilDepartment of Biochemistry and Molecular Biology II, School of Pharmacy, "José Mataix Verdú" Institute of Nutrition and Food Technology (INYTA), University of Granada, 18016 Granada, Spain.ORCID 0000-0001-7663-0939
Mercedes Gil-CamposMetabolism and Investigation Unit, Reina Sofia University Hospital, Maimonides Institute of Biomedicine Research of Cordoba (IMIBIC), University of Cordoba, 14004 Cordoba, Spain.ORCID 0000-0002-9007-0242

Funding

Modalidad Retos Consolidado. Dirección General de Investigación y Transferencia del Conocimiento. Consejería de Economía, Conocimiento, Empresas y Universidad. Junta de Andalucía, Spain PY18-1802
6 · The paper itself

Abstract

Children with a history of extrauterine growth restriction (EUGR), later at prepubertal age, exhibit an increased metabolic risk including risen insulin resistance and low-grade inflammation. However, the progression of such metabolic changes after puberty and the lasting health implications have not yet been investigated. The objective of this study was to ascertain whether young adults with a history of EUGR faced increased vulnerability to metabolic disorders. A study was conducted comparing a group of adults with a history of EUGR with a healthy reference group. A total of 110 young adults (36 from the EUGR group and 74 from the control group) were included. Anthropometric variables, blood pressure (BP), general biochemical parameters, plasma inflammatory biomarkers, and adipokines were assessed. Compared to the reference group, the EUGR group had a shorter height and body weight with higher lean mass and waist circumference, as well as a greater percentage of individuals with high BP. In addition, EUGR patients had higher values of insulin, HOMA-IR, nerve growth factor, and leptin, and lower levels of adiponectin and resistin. The present study suggests that young adults with a history of EUGR present increased metabolic risk factors therefore, clinical follow-up should be considered.

Indexed as

InflammationAdipokinesAdultBiomarkersBlood PressureFemaleGrowth DisordersHumansInsulin ResistanceMaleRisk FactorsYoung AdultAdipokinesBiomarkersadipokinesextrauterine growth restrictioninflammationinsulin resistancemetabolismnutrition

Identifiers

PMID38892541
PMCPMC11174372

What Socratic holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.