Evidence map›Paper›PMID 38893088›Full record

ReviewCancers2024

Extracellular Vesicles in Lung Cancer: Implementation in Diagnosis and Therapeutic Perspectives.

Anna Paola Carreca, Rosaria Tinnirello, Vitale Miceli, Antonio Galvano, Valerio Gristina, Lorena Incorvaia, Mariangela Pampalone, Simona Taverna, Gioacchin Iannolo

Abstract readReview
In one paragraph

Review in Cancers, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 17 papers.

0numbers the graph read from it
0cells of the map it votes in
17citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

17 citing papers in PubMed.

  1. Review
  2. Review
  3. Review
  4. Article
  5. Review
  6. Review
  7. Article
  8. Review
  9. Article
  10. Article
  11. Review
  12. Article
  13. Connecting the dots: (RANKLTranslational lung cancer research · 2025
    Article
  14. Review
  15. Article
  16. Review
  17. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors.

Anna Paola CarrecaRi.MED Foundation, 90127 Palermo, Italy.ORCID 0000-0002-7389-7555
Rosaria TinnirelloDepartment of Research, IRCCS ISMETT (Istituto Mediterraneo per i Trapianti e Terapie ad Alta Specializzazione), Via E. Tricomi 5, 90127 Palermo, Italy.ORCID 0000-0002-4324-5097
Vitale MiceliDepartment of Research, IRCCS ISMETT (Istituto Mediterraneo per i Trapianti e Terapie ad Alta Specializzazione), Via E. Tricomi 5, 90127 Palermo, Italy.ORCID 0000-0001-8922-9909
Antonio GalvanoDepartment of Precision Medicine in Medical, Surgical and Critical Care, University of Palermo, 90133 Palermo, Italy.ORCID 0000-0003-4365-5683
Valerio GristinaDepartment of Precision Medicine in Medical, Surgical and Critical Care, University of Palermo, 90133 Palermo, Italy.
Lorena IncorvaiaDepartment of Precision Medicine in Medical, Surgical and Critical Care, University of Palermo, 90133 Palermo, Italy.ORCID 0000-0002-1199-7286
Mariangela PampaloneRi.MED Foundation, 90127 Palermo, Italy.ORCID 0000-0001-6076-6831
Simona TavernaInstitute of Translational Pharmacology (IFT), National Research Council (CNR), 90146 Palermo, Italy.ORCID 0000-0002-2192-8938
Gioacchin IannoloDepartment of Research, IRCCS ISMETT (Istituto Mediterraneo per i Trapianti e Terapie ad Alta Specializzazione), Via E. Tricomi 5, 90127 Palermo, Italy.ORCID 0000-0002-7710-4735

Funding

RT, VM and GI work was supported by the Italian Ministry of Health, Ricerca Corrente. 0000
6 · The paper itself

Abstract

Lung cancer represents the leading cause of cancer-related mortality worldwide, with around 1.8 million deaths in 2020. For this reason, there is an enormous interest in finding early diagnostic tools and novel therapeutic approaches, one of which is extracellular vesicles (EVs). EVs are nanoscale membranous particles that can carry proteins, lipids, and nucleic acids (DNA and RNA), mediating various biological processes, especially in cell-cell communication. As such, they represent an interesting biomarker for diagnostic analysis that can be performed easily by liquid biopsy. Moreover, their growing dataset shows promising results as drug delivery cargo. The aim of our work is to summarize the recent advances in and possible implications of EVs for early diagnosis and innovative therapies for lung cancer.

Indexed as

BALFEVsliquid biopsylung cancerNSCLCorgan failurepersonalized medicineSCLC

Identifiers

PMID38893088
PMCPMC11171234

What Socratic holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.