Evidence map›Paper›PMID 38893271›Full record

ArticleCancers2024

Cholesterol Dietary Intake and Tumor Cell Homeostasis Drive Early Epithelial Tumorigenesis: A Potential Modelization of Early Prostate Tumorigenesis.

Marine Vialat, Elissa Baabdaty, Amalia Trousson, Ayhan Kocer, Jean-Marc A Lobaccaro, Silvère Baron, Laurent Morel, Cyrille de Joussineau

Abstract read
In one paragraph

Article in Cancers, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Review
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Marine VialatGReD, CNRS UMR6293, Inserm U1103, Université Clermont Auvergne, 28 Place Henri Dunant, BP38, F63001 Clermont-Ferrand, France.ORCID 0000-0001-7093-1175
Elissa BaabdatyGReD, CNRS UMR6293, Inserm U1103, Université Clermont Auvergne, 28 Place Henri Dunant, BP38, F63001 Clermont-Ferrand, France.
Amalia TroussonGReD, CNRS UMR6293, Inserm U1103, Université Clermont Auvergne, 28 Place Henri Dunant, BP38, F63001 Clermont-Ferrand, France.ORCID 0000-0001-6587-9501
Ayhan KocerGReD, CNRS UMR6293, Inserm U1103, Université Clermont Auvergne, 28 Place Henri Dunant, BP38, F63001 Clermont-Ferrand, France.
Jean-Marc A LobaccaroGReD, CNRS UMR6293, Inserm U1103, Université Clermont Auvergne, 28 Place Henri Dunant, BP38, F63001 Clermont-Ferrand, France.ORCID 0000-0001-9890-2392
Silvère BaronGReD, CNRS UMR6293, Inserm U1103, Université Clermont Auvergne, 28 Place Henri Dunant, BP38, F63001 Clermont-Ferrand, France.ORCID 0000-0002-4524-3087
Laurent MorelGReD, CNRS UMR6293, Inserm U1103, Université Clermont Auvergne, 28 Place Henri Dunant, BP38, F63001 Clermont-Ferrand, France.
Cyrille de JoussineauGReD, CNRS UMR6293, Inserm U1103, Université Clermont Auvergne, 28 Place Henri Dunant, BP38, F63001 Clermont-Ferrand, France.ORCID 0000-0002-2488-2760

Funding

Fondation ARC pour la Recherche sur le Cancer 4 ème année de thèseFrench Foundation Centre FC.3R Re-InnovLa Ligue Contre le Cancer projet cholesterol
6 · The paper itself

Abstract

Epidemiological studies point to cholesterol as a possible key factor for both prostate cancer incidence and progression. It could represent a targetable metabolite as the most aggressive tumors also appear to be sensitive to therapies designed to decrease hypercholesterolemia, such as statins. However, it remains unknown whether and how cholesterol, through its dietary uptake and its metabolism, could be important for early tumorigenesis. Oncogene clonal induction in the

Indexed as

basal extrusioncholesterolearly tumorigenesisprostate cancer

Identifiers

PMID38893271
PMCPMC11172085

What Socratic holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.