Evidence map›Paper›PMID 38893333›Full record

ArticleMolecules (Basel, Switzerland)2024

In Vitro and Molecular Docking Evaluation of the Anticholinesterase and Antidiabetic Effects of Compounds from

Romeo Toko Feunaing, Alfred Ngenge Tamfu, Abel Joel Yaya Gbaweng, Selcuk Kucukaydin, Joseph Tchamgoue, Alain Meli Lannang, Bruno Ndjakou Lenta, Simeon Fogue Kouam, Mehmet Emin Duru, El Hassane Anouar and 2 more

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Molecules (Basel, Switzerland), 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

6 citing papers in PubMed.

  1. Article
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  5. Review
  6. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

12 authors.

Romeo Toko FeunaingDepartment of Chemistry, Faculty of Sciences, University of Ngaoundere, Ngaoundere P.O. Box 454, Cameroon.ORCID 0009-0003-8690-9660
Alfred Ngenge TamfuDepartment of Chemical Engineering, School of Chemical Engineering and Mineral Industries, University of Ngaoundere, Ngaoundere P.O. Box 454, Cameroon.ORCID 0000-0001-6683-3337
Abel Joel Yaya GbawengDepartment of Chemistry, Faculty of Sciences, University of Ngaoundere, Ngaoundere P.O. Box 454, Cameroon.
Selcuk KucukaydinDepartment of Medical Services and Techniques, Koycegiz Vocational School of Health Services, Mugla Sitki Kocman University, 48800 Mugla, Turkey.ORCID 0000-0001-8538-6528
Joseph TchamgoueDepartment of Chemistry, Higher Teacher Training College, The University of Yaoundé 1, Yaoundé P.O. Box 47, Cameroon.ORCID 0000-0002-0506-9678
Alain Meli LannangDepartment of Chemical Engineering, School of Chemical Engineering and Mineral Industries, University of Ngaoundere, Ngaoundere P.O. Box 454, Cameroon.ORCID 0000-0001-5422-0357
Bruno Ndjakou LentaDepartment of Chemistry, Higher Teacher Training College, The University of Yaoundé 1, Yaoundé P.O. Box 47, Cameroon.
Simeon Fogue KouamDepartment of Chemistry, Higher Teacher Training College, The University of Yaoundé 1, Yaoundé P.O. Box 47, Cameroon.ORCID 0000-0003-0191-0527
Mehmet Emin DuruDepartment of Chemistry, Faculty of Science, Mugla Sitki Kocman University, 48000 Mugla, Turkey.
El Hassane AnouarDepartment of Chemistry, College of Sciences and Humanities in Al-Kharj, Prince Sattam bin Ab-dulaziz University, Al-Kharj P.O. Box 83, Saudi Arabia.ORCID 0000-0001-9240-7163
Emmanuel TallaDepartment of Chemistry, Faculty of Sciences, University of Ngaoundere, Ngaoundere P.O. Box 454, Cameroon.
Rodica Mihaela DinicaDepartment of Chemistry, Physics and Environment, Faculty of Sciences and Environment, 'Dunarea de Jos University', 47 Domneasca Str., 800008 Galati, Romania.ORCID 0000-0002-2126-0931

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Alzheimer's disease (AD) and diabetes are non-communicable diseases with global impacts. Inhibitors of acetylcholinesterase (AChE) and butyrylcholinesterase (BChE) are suitable therapies for AD, while α-amylase and α-glucosidase inhibitors are employed as antidiabetic agents. Compounds were isolated from the medicinal plant

Indexed as

Acetylcholinesterasealpha-AmylasesCholinesterase InhibitorsHypoglycemic AgentsMolecular Docking SimulationPlant ExtractsTerminaliaalpha-GlucosidasesButyrylcholinesteraseGlycoside Hydrolase InhibitorsHumansMolecular StructureAcetylcholinesterasealpha-Amylasesalpha-GlucosidasesButyrylcholinesteraseCholinesterase InhibitorsGlycoside Hydrolase InhibitorsHypoglycemic AgentsPlant ExtractsAlzheimer’s diseasecholinesterase inhibitiondiabetesmolecular dockingTerminalia macropteraα-amylase inhibitionα-glucosidase inhibition

Identifiers

PMID38893333
PMCPMC11174011

What Socratic holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.