Evidence mapPaperPMID 38893720Full record

ArticleDiagnostics (Basel, Switzerland)2024

Sodium-Glucose Cotransporter 2 Inhibitor Combined with Conventional Diuretics Ameliorate Body Fluid Retention without Excessive Plasma Volume Reduction.

Maki Asakura-Kinoshita, Takahiro Masuda, Kentaro Oka, Ken Ohara, Marina Miura, Masato Morinari, Kyohei Misawa, Yasuharu Miyazawa, Tetsu Akimoto, Kazuyuki Shimada and 1 more

Abstract read
In one paragraph

Article in Diagnostics (Basel, Switzerland), 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 10 papers.

0numbers the graph read from it
0cells of the map it votes in
10citing papers in PubMed
field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

10 citing papers in PubMed.

  1. Article
  2. Article
  3. Article
  4. Article
  5. Article
  6. Review
  7. Article
  8. Review
  9. Water and sodium conservation response induced by SGLT2 inhibitor ipragliflozin in Dahl salt-sensitive hypertensive rats.Hypertension research : official journal of the Japanese Society of Hypertension · 2024
    Article
  10. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors.

Maki Asakura-KinoshitaDivision of Nephrology, Department of Internal Medicine, Jichi Medical University, Shimotsuke 3290498, Japan.
Takahiro MasudaDivision of Nephrology, Department of Internal Medicine, Jichi Medical University, Shimotsuke 3290498, Japan.ORCID 0000-0002-6893-7188
Kentaro OkaDivision of Nephrology, Department of Internal Medicine, Jichi Medical University, Shimotsuke 3290498, Japan.
Ken OharaDivision of Nephrology, Department of Internal Medicine, Jichi Medical University, Shimotsuke 3290498, Japan.
Marina MiuraDepartment of Nephrology, Shin-Oyama City Hospital, Oyama 3230827, Japan.
Masato MorinariDepartment of Internal Medicine, Nasu Minami Hospital, Nasu-Karasuyama 3210621, Japan.
Kyohei MisawaDivision of Nephrology, Department of Internal Medicine, Jichi Medical University, Shimotsuke 3290498, Japan.
Yasuharu MiyazawaDepartment of Internal Medicine, Nasu Minami Hospital, Nasu-Karasuyama 3210621, Japan.
Tetsu AkimotoDivision of Nephrology, Department of Internal Medicine, Jichi Medical University, Shimotsuke 3290498, Japan.
Kazuyuki ShimadaDepartment of Cardiology, Shin-Oyama City Hospital, Oyama 3230827, Japan.
Daisuke NagataDivision of Nephrology, Department of Internal Medicine, Jichi Medical University, Shimotsuke 3290498, Japan.

Funding

Japan Kidney Foundation JKFB21-18
6 · The paper itself

Abstract

We previously reported that sodium-glucose cotransporter 2 (SGLT2) inhibitors exert sustained fluid homeostatic actions through compensatory increases in osmotic diuresis-induced vasopressin secretion and fluid intake. However, SGLT2 inhibitors alone do not produce durable amelioration of fluid retention. In this study, we examined the comparative effects of the SGLT2 inhibitor dapagliflozin (SGLT2i group,

Indexed as

cardiorenal protectioncopeptinextracellular waterfluid retentionheart failureinterstitial fluidloop diureticplasma volumesodium–glucose cotransporter 2 (SGLT2) inhibitorvasopressin

Identifiers

PMID38893720
PMCPMC11171863

What Socratic holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.