Evidence map›Paper›PMID 38894746›Full record

ArticleFrontiers in endocrinology2024

Differential involvement of cAMP/PKA-, PLC/PKC- and Ca

Wensheng Li, Cheng Ye, Mulan He, Wendy K W Ko, Christopher H K Cheng, Ying Wai Chan, Anderson O L Wong

Abstract read
In one paragraph

Article in Frontiers in endocrinology, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Review
  2. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Wensheng Li *School of Biological Sciences, The University of Hong Kong, Hong Kong, Hong Kong SAR, China.
Cheng Ye *School of Biological Sciences, The University of Hong Kong, Hong Kong, Hong Kong SAR, China.
Mulan HeSchool of Biological Sciences, The University of Hong Kong, Hong Kong, Hong Kong SAR, China.
Wendy K W KoSchool of Biological Sciences, The University of Hong Kong, Hong Kong, Hong Kong SAR, China.
Christopher H K ChengSchool of Biomedical Sciences, Chinese University of Hong Kong, Hong Kong, Hong Kong SAR, China.
Ying Wai ChanSchool of Biological Sciences, The University of Hong Kong, Hong Kong, Hong Kong SAR, China.
Anderson O L WongSchool of Biological Sciences, The University of Hong Kong, Hong Kong, Hong Kong SAR, China.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Gonadotropin-releasing hormone (GnRH) is a key stimulator for gonadotropin secretion in the pituitary and its pivotal role in reproduction is well conserved in vertebrates. In fish models, GnRH can also induce prolactin (PRL) release, but little is known for the corresponding effect on PRL gene expression as well as the post-receptor signalling involved. Using grass carp as a model, the functional role of GnRH and its underlying signal transduction for PRL regulation were examined at the pituitary level. Using laser capture microdissection coupled with RT-PCR, GnRH receptor expression could be located in carp lactotrophs. In primary cell culture prepared from grass carp pituitaries, the native forms of GnRH, GnRH2 and GnRH3, as well as the GnRH agonist [D-Arg

Indexed as

CalciumCarpsCyclic AMPCyclic AMP-Dependent Protein KinasesGonadotropin-Releasing HormonePituitary GlandProlactinProtein Kinase CType C PhospholipasesAnimalsCalmodulinCells, CulturedGene ExpressionSignal TransductionCalciumCalmodulinCyclic AMPCyclic AMP-Dependent Protein KinasesGonadotropin-Releasing HormoneProlactinProtein Kinase CType C Phospholipasesgene expressionGnRHgrass carphormone secretionpituitary cellsprolactinsignal transduction

Identifiers

PMID38894746
PMCPMC11183098

What Socratic holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.