Evidence map›Paper›PMID 38895294›Full record

ArticlebioRxiv : the preprint server for biology2024

Uncoupling the CRMP2-Ca

Heather N Allen, Sara Hestehave, Paz Duran, Tyler S Nelson, Rajesh Khanna

Abstract readPreprint
PubMed Full text at PMC Publisher
In one paragraph

Article in bioRxiv : the preprint server for biology, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

5 authors.

Heather N AllenDepartment of Pharmacology & Therapeutics, University of Florida College of Medicine, Gainesville, Florida 32610, USA.ORCID 0000-0003-0771-1959
Sara HestehaveDepartment of Molecular Pathobiology, College of Dentistry, New York University, New York, New York 10010, USA.ORCID 0000-0002-1837-521X
Paz DuranDepartment of Molecular Pathobiology, College of Dentistry, New York University, New York, New York 10010, USA.ORCID 0000-0001-8729-8636
Tyler S NelsonDepartment of Pharmacology & Therapeutics, University of Florida College of Medicine, Gainesville, Florida 32610, USA.ORCID 0000-0002-6675-4820
Rajesh KhannaDepartment of Pharmacology & Therapeutics, University of Florida College of Medicine, Gainesville, Florida 32610, USA.ORCID 0000-0002-9066-2969

Funding

Sentrin proteases, CRMP2 deSUMOylation, and Chronic PainR01NS120663 · NINDS · UNIVERSITY OF FLORIDA · PI KHANNA, RAJESH · 2020 to 2021
$2.6M
Validation of Neuropilin-1 Receptor Signaling in Nociceptive ProcessingRF1NS131165 · NINDS · UNIVERSITY OF FLORIDA · PI KHANNA, RAJESH · 2023 to 2023
$2.0M
Antagonists of CRMP2 Phosphorylation for Chemotherapy-Induced Peripheral NeuropathyR61NS126026 · NINDS · UNIVERSITY OF FLORIDA · PI KHANNA, RAJESH · 2022 to 2022
$1.4M
Dissecting the Parabrachial Nucleus’s Role in the Development and Maintenance of Neuropathic PainK00NS124190 · NINDS · UNIVERSITY OF FLORIDA · PI Tyler Scott Nelson · 2023 to 2026
$346k
Neuropeptide Y1 Receptor-Expressing Neurons in the Lateral Parabrachial Nucleus in Neuropathic PainF32NS128392 · NINDS · UNIVERSITY OF FLORIDA · PI ALLEN, HEATHER NOEL · 2023 to 2025
$217k
NINDS NIH HHS F32 NS128392NINDS NIH HHS K00 NS124190NINDS NIH HHS R01 NS120663NINDS NIH HHS R61 NS126026NINDS NIH HHS RF1 NS131165
6 · The paper itself

Abstract

Osteoarthritis (OA) represents a significant pain challenge globally, as current treatments are limited and come with substantial and adverse side effects. Voltage-gated calcium channels have proved to be pharmacologically effective targets, with multiple FDA-approved Ca

Identifiers

PMID38895294
PMCPMC11185632

What Socratic holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.