Evidence map›Paper›PMID 38895629›Full record

ArticleFrontiers in pharmacology2024

Influence of β-lactam pharmacodynamics on the systems microbiology of gram-positive and gram-negative polymicrobial communities.

Nicholas M Smith, Harpreet Kaur, Ravneet Kaur, Trisha Minoza, Michael Kent, Ayeh Barekat, Justin R Lenhard

Abstract read
In one paragraph

Article in Frontiers in pharmacology, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Nicholas M SmithSchool of Pharmacy and Pharmaceutical Sciences, University at Buffalo, Buffalo, NY, United States.
Harpreet KaurCalifornia Northstate University College of Pharmacy, Elk Grove, CA, United States.
Ravneet KaurCalifornia Northstate University College of Pharmacy, Elk Grove, CA, United States.
Trisha MinozaCalifornia Northstate University College of Pharmacy, Elk Grove, CA, United States.
Michael KentCalifornia Northstate University College of Pharmacy, Elk Grove, CA, United States.
Ayeh BarekatCalifornia Northstate University College of Pharmacy, Elk Grove, CA, United States.
Justin R LenhardCalifornia Northstate University College of Pharmacy, Elk Grove, CA, United States.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Objectives: We sought to evaluate the pharmacodynamics of β-lactam antibacterials against polymicrobial communities of clinically relevant gram-positive and gram-negative pathogens. Methods: Two Results: In the integrated analysis, the maximum killing of ampicillin (E Discussion: β-lactamase-producing

Indexed as

beta-lactamEnterococcus faecalisEscherichia colimechanism-based modelingpharmacodynamicpolymicrobialStaphylococcus aureussystems microbiology

Identifiers

PMID38895629
PMCPMC11183306

What Socratic holds

Textmetadata
LicenceCC BY
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.