Evidence map›Paper›PMID 38896221›Full record

ArticleProbiotics and antimicrobial proteins2025

Heat-Killed Lactococcus Lactis KC24 Ameliorates Scopolamine-Induced Memory Impairment in ICR Mice.

Na-Kyoung Lee, Yunjung Lee, Ji Ye Park, Eunju Park, Hyun-Dong Paik

Abstract read
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In one paragraph

Article in Probiotics and antimicrobial proteins, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed.

  1. Preventive Effect of ProbioticAntioxidants (Basel, Switzerland) · 2025
    Article
  2. Effect ofNutrients · 2025
    Article
  3. Heat-KilledJournal of microbiology and biotechnology · 2025
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Na-Kyoung LeeDepartment of Food Science and Biotechnology of Animal Resources, Konkuk University, Seoul, 05029, Korea.
Yunjung LeeDepartment of Food and Nutrition, Kyungnam University, Changwon, 51767, Korea.
Ji Ye ParkDepartment of Food and Nutrition, Kyungnam University, Changwon, 51767, Korea.
Eunju ParkDepartment of Food and Nutrition, Kyungnam University, Changwon, 51767, Korea. pej@kyungnam.ac.kr.
Hyun-Dong PaikDepartment of Food Science and Biotechnology of Animal Resources, Konkuk University, Seoul, 05029, Korea. hdpaik@konkuk.ac.kr.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Heat-killed Lactococcus lactis KC24 (H-KC24) has been examined for its neuroprotective effects in SH-SY5Y cells. We hypothesized that H-KC24 could alleviate memory impairment through the gut-brain axis. Scopolamine (1 mg/kg/day) was administered to ICR mice to induce memory impairment. Low- and high-dose H-KC24 cells (1 × 10

Indexed as

Lactococcus lactisMemory DisordersProbioticsScopolamineAcetylcholinesteraseAnimalsBrainBrain-Derived Neurotrophic FactorHot TemperatureMaleMiceMice, Inbred ICRAcetylcholinesteraseBrain-Derived Neurotrophic FactorScopolamineAnimal modelLactococcus lactisMemoryNeuroprotective effectProbiotics

Identifiers

PMID38896221

What Socratic holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.