Evidence map›Paper›PMID 38899301›Full record

ReviewWorld journal of clinical cases2024

Advanced nanomedicines and immunotherapeutics to treat respiratory diseases especially COVID-19 induced thrombosis.

Jie Wu, Ying Zheng, Li-Na Zhang, Cai-Li Gu, Wang-Li Chen, Min-Qiang Chang

Abstract readReview
In one paragraph

Review in World journal of clinical cases, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Jie WuDepartment of Respiratory and Oncology, 72 Group Army Hospital of PLA, Huzhou 313000, Zhejiang Province, China.
Ying ZhengDepartment of Respiratory and Oncology, 72 Group Army Hospital of PLA, Huzhou 313000, Zhejiang Province, China.
Li-Na ZhangDepartment of Respiratory and Oncology, 72 Group Army Hospital of PLA, Huzhou 313000, Zhejiang Province, China.
Cai-Li GuDepartment of Respiratory and Oncology, 72 Group Army Hospital of PLA, Huzhou 313000, Zhejiang Province, China.
Wang-Li ChenDepartment of Respiratory and Oncology, 72 Group Army Hospital of PLA, Huzhou 313000, Zhejiang Province, China.
Min-Qiang ChangDepartment of Otorhinolaryngology, 72 Group Army Hospital of PLA, Huzhou 313000, Zhejiang Province, China. cmqent98@163.com.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Immunotherapy and associated immune regulation strategies gained huge attraction in order to be utilized for treatment and prevention of respiratory diseases. Engineering specifically nanomedicines can be used to regulate host immunity in lungs in the case of respiratory diseases including coronavirus disease 2019 (COVID-19) infection. COVID-19 causes pulmonary embolisms, thus new therapeutic options are required to target thrombosis, as conventional treatment options are either not effective due to the complexity of the immune-thrombosis pathophysiology. In this review, we discuss regulation of immune response in respiratory diseases especially COVID-19. We further discuss thrombosis and provide an overview of some antithrombotic nanoparticles, which can be used to develop nanomedicine against thrombo-inflammation induced by COVID-19 and other respiratory infectious diseases. We also elaborate the importance of immunomodulatory nanomedicines that can block pro-inflammatory signalling pathways, and thus can be recommended to treat respiratory infectious diseases.

Indexed as

COVID-19ImmunotherapeuticsNanomedicinesRespiratory diseasesThrombosis

Identifiers

PMID38899301
PMCPMC11185334

What Socratic holds

Textmetadata
LicenceCC BY-NC
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.